Active: Autoimmune disease Clear all

GWAS 2024-11-15

A genome-wide cross-trait analysis identifying shared genetic basis and causal relationships between Hunner-type interstitial cystitis and autoimmune diseases in East Asian populations.

Lyu X, Peng L et al.

Front Immunol

Purpose: Epidemiological studies have demonstrated the clinical link between Hunner interstitial cys...

Hunner-type interstitial cystitis or atopic dermatitis (MTAG)

190904

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-12

Genetic drivers and cellular selection of female mosaic X chromosome loss.

Liu A, Genovese G et al.

Nature

Mosaic loss of the X chromosome (mLOX) is the most common clonal somatic alteration in leukocytes of...

Mosaic loss of chromosome X

806257

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-15

Oral and non-oral lichen planus show genetic heterogeneity and differential risk for autoimmune disease and oral cancer.

Reeve MP, Vehviläinen M et al.

Am J Hum Genet

Lichen planus (LP) is a T-cell-mediated inflammatory disease affecting squamous epithelia in many pa...

ICD10 L43: Lichen planus

412090

Participants

N/A

Studies

Details PubMed

GWAS 2024-04-15

Shared genetic architecture between autoimmune disorders and B-cell acute lymphoblastic leukemia: insights from large-scale genome-wide cross-trait analysis.

Yu X, Chen Y et al.

BMC Med

To study the shared genetic structure between autoimmune diseases and B-cell acute lymphoblastic leu...

B-cell lymphoblastic leukemia or adult-onset asthma (pleiotropy)

349240

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-07

A multi-ancestry genome-wide association study in type 1 diabetes.

Michalek DA, Tern C et al.

Hum Mol Genet

Type 1 diabetes (T1D) is an autoimmune disease caused by destruction of the pancreatic β-cells. Geno...

Type 1 diabetes

308

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-27

Genome-wide meta-analysis identifies 11 susceptibility variants of vitiligo in the Chinese Han population.

Wang D, Chen W et al.

J Invest Dermatol

Vitiligo is an autoimmune disease involving loss of melanocytes. Although several genetic studies ha...

Vitiligo

13327

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-27

Citrullinated and MMP-degraded vimentin is associated with chronic pulmonary diseases and genetic variants in PADI3/PADI4 and CFH in postmenopausal women.

Bager CL, Blair JPM et al.

Sci Rep

Citrullinated vimentin has been linked to several chronic and autoimmune diseases, but how citrullin...

Citrullinated and MMP-degraded vimentin

4369

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-21

Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles.

Yang JS, Liu TY et al.

Clin Cosmet Investig Dermatol

Purpose: Alopecia areata (AA) is one of the most prevalent autoimmune diseases affecting humans. Giv...

Alopecia areata

8575

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-28

Locus for severity implicates CNS resilience in progression of multiple sclerosis.

International Multiple Sclerosis Genetics Consortium

Nature

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that results in...

Age-related multiple sclerosis severity score

Replicated

22389

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-12

Identifying shared genetic loci and common risk genes of rheumatoid arthritis associated with three autoimmune diseases based on large-scale cross-trait genome-wide association studies.

Wen YP, Yu ZG

Front Immunol

Introduction: Substantial links between autoimmune diseases have been shown by an increasing number ...

Rheumatoid arthritis or multiple sclerosis

453670

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-15

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy.

Ollila HM, Sharon E et al.

Nat Commun

Narcolepsy type 1 (NT1) is caused by a loss of hypocretin/orexin transmission. Risk factors include ...

Type 1 narcolepsy

90929

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-01

Genetic Associations Between Stress-Related Disorders and Autoimmune Disease.

Zeng Y, Suo C et al.

Am J Psychiatry

Objective: Emerging evidence supports a bidirectional phenotypic association between stress-related ...

Autoimmune disease

376871

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide cross-trait analysis identifying shared genetic basis and causal relationships between Hunner-type interstitial cystitis and autoimmune diseases in East Asian populations.

Lyu X, Peng L et al.

Front Immunol

Hunner-type interstitial cystitis or atopic dermatitis (MTAG)

2024-11-15

Genetic drivers and cellular selection of female mosaic X chromosome loss.

Liu A, Genovese G et al.

Nature

Mosaic loss of chromosome X

2024-06-12

Oral and non-oral lichen planus show genetic heterogeneity and differential risk for autoimmune disease and oral cancer.

Reeve MP, Vehviläinen M et al.

Am J Hum Genet

ICD10 L43: Lichen planus

2024-05-15

Shared genetic architecture between autoimmune disorders and B-cell acute lymphoblastic leukemia: insights from large-scale genome-wide cross-trait analysis.

Yu X, Chen Y et al.

BMC Med

B-cell lymphoblastic leukemia or adult-onset asthma (pleiotropy)

2024-04-15

A multi-ancestry genome-wide association study in type 1 diabetes.

Michalek DA, Tern C et al.

Hum Mol Genet

Type 1 diabetes

2024-03-07

Genome-wide meta-analysis identifies 11 susceptibility variants of vitiligo in the Chinese Han population.

Wang D, Chen W et al.

J Invest Dermatol

Vitiligo

2024-01-27

Citrullinated and MMP-degraded vimentin is associated with chronic pulmonary diseases and genetic variants in PADI3/PADI4 and CFH in postmenopausal women.

Bager CL, Blair JPM et al.

Sci Rep

Citrullinated and MMP-degraded vimentin

2023-12-27

Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles.

Yang JS, Liu TY et al.

Clin Cosmet Investig Dermatol

Alopecia areata

2023-09-21

Locus for severity implicates CNS resilience in progression of multiple sclerosis.

International Multiple Sclerosis Genetics Consortium

Nature

Age-related multiple sclerosis severity score

2023-06-28

Identifying shared genetic loci and common risk genes of rheumatoid arthritis associated with three autoimmune diseases based on large-scale cross-trait genome-wide association studies.

Wen YP, Yu ZG

Front Immunol

Rheumatoid arthritis or multiple sclerosis

2023-06-12

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy.

Ollila HM, Sharon E et al.

Nat Commun

Type 1 narcolepsy

2023-05-15

Genetic Associations Between Stress-Related Disorders and Autoimmune Disease.

Zeng Y, Suo C et al.

Am J Psychiatry

Autoimmune disease

2023-04-01