Active: Celiac disease Clear all

GWAS 2019-10-07

Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease.

Ricaño-Ponce I, Gutierrez-Achury J et al.

Eur J Hum Genet

Celiac disease (CeD) is a common immune-mediated disease of the small intestine that is triggered by...

Celiac disease

27774

Participants

N/A

Studies

Details PubMed

GWAS 2018-05-21

A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease.

Hrdlickova B, Mulder CJ et al.

Eur J Gastroenterol Hepatol

Approximately 5% of patients with celiac disease (CeD) do not respond to a gluten-free diet and prog...

Refractory celiac disease type II

Replicated

2225

Participants

N/A

Studies

Details PubMed

GWAS 2016-01-01

Functional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritis.

Gutierrez-Achury J, Zorro MM et al.

Hum Mol Genet

Hundreds of genomic loci have been associated with a significant number of immune-mediated diseases,...

Celiac disease and Rheumatoid arthritis

46684

Participants

N/A

Studies

Details PubMed

GWAS 2015-04-29

Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci.

Coleman C, Quinn EM et al.

Eur J Hum Genet

Coeliac disease (CD) is a chronic immune-mediated disease triggered by the ingestion of gluten. It h...

Celiac disease

Replicated

25147

Participants

N/A

Studies

Details PubMed

GWAS 2014-07-07

Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus.

Garner C, Ahn R et al.

PLoS One

We performed a genome-wide association study (GWAS) of 1550 North American celiac disease cases and ...

Celiac disease

4634

Participants

N/A

Studies

Details PubMed

GWAS 2014-07-01

Genome-wide genetic and transcriptomic investigation of variation in antibody response to dietary antigens.

Rubicz R, Yolken R et al.

Genet Epidemiol

Increased immunoglobulin G (IgG) response to dietary antigens can be associated with gastrointestina...

Food antigen IgG levels

1367

Participants

N/A

Studies

Details PubMed

GWAS 2013-08-02

A possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac disease.

Östensson M, Montén C et al.

PLoS One

Celiac disease is a common autoimmune disorder characterized by an intestinal inflammation triggered...

Celiac disease

618

Participants

N/A

Studies

Details PubMed

GWAS 2013-01-31

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

Lauc G, Huffman JE et al.

PLoS Genet

Glycosylation of immunoglobulin G (IgG) influences IgG effector function by modulating binding to Fc...

IgG glycosylation

2247

Participants

N/A

Studies

Details PubMed

GWAS 2011-11-06

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease.

Trynka G, Hunt KA et al.

Nat Genet

Using variants from the 1000 Genomes Project pilot European CEU dataset and data from additional res...

Celiac disease

24269

Participants

N/A

Studies

Details PubMed

GWAS 2011-02-24

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

Zhernakova A, Stahl EA et al.

PLoS Genet

Epidemiology and candidate gene studies indicate a shared genetic basis for celiac disease (CD) and ...

Celiac disease or Rheumatoid arthritis

Replicated

50266

Participants

N/A

Studies

Details PubMed

GWAS 2011-01-27

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease.

Festen EA, Goyette P et al.

PLoS Genet

Crohn's disease (CD) and celiac disease (CelD) are chronic intestinal inflammatory diseases, involvi...

Crohn's disease and celiac disease

Replicated

21616

Participants

N/A

Studies

Details PubMed

GWAS 2010-02-28

Multiple common variants for celiac disease influencing immune gene expression.

Dubois PC, Trynka G et al.

Nat Genet

We performed a second-generation genome-wide association study of 4,533 individuals with celiac dise...

Celiac disease

Replicated

25885

Participants

N/A

Studies

Details PubMed

Title

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Date

Actions

Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease.

Ricaño-Ponce I, Gutierrez-Achury J et al.

Eur J Hum Genet

Celiac disease

2019-10-07

A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease.

Hrdlickova B, Mulder CJ et al.

Eur J Gastroenterol Hepatol

Refractory celiac disease type II

2018-05-21

Functional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritis.

Gutierrez-Achury J, Zorro MM et al.

Hum Mol Genet

Celiac disease and Rheumatoid arthritis

2016-01-01

Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci.

Coleman C, Quinn EM et al.

Eur J Hum Genet

Celiac disease

2015-04-29

Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus.

Garner C, Ahn R et al.

PLoS One

Celiac disease

2014-07-07

Genome-wide genetic and transcriptomic investigation of variation in antibody response to dietary antigens.

Rubicz R, Yolken R et al.

Genet Epidemiol

Food antigen IgG levels

2014-07-01

A possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac disease.

Östensson M, Montén C et al.

PLoS One

Celiac disease

2013-08-02

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

Lauc G, Huffman JE et al.

PLoS Genet

IgG glycosylation

2013-01-31

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease.

Trynka G, Hunt KA et al.

Nat Genet

Celiac disease

2011-11-06

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

Zhernakova A, Stahl EA et al.

PLoS Genet

Celiac disease or Rheumatoid arthritis

2011-02-24

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease.

Festen EA, Goyette P et al.

PLoS Genet

Crohn's disease and celiac disease

2011-01-27

Multiple common variants for celiac disease influencing immune gene expression.

Dubois PC, Trynka G et al.

Nat Genet

Celiac disease

2010-02-28