Active: Depressive symptoms Clear all

GWAS 2024-10-29

Whole exome sequencing identified six novel genes for depressive symptoms.

Li ZY, Fei CJ et al.

Mol Psychiatry

Previous genome-wide association studies of depression have primarily focused on common variants, li...

Depressive symptoms (sum-score)

296199

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-15

Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom Trajectory.

Ohseto H, Takahashi I et al.

Depress Anxiety

This study is aimed at revealing the risk factors, prognosis, influence on offspring, and genetic ar...

Perinatal depression

5098

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-06

Genome-wide association study implicates the role of TBXAS1 in the pathogenesis of depressive symptoms among the Korean population.

Park K, Do AR et al.

Transl Psychiatry

Although depression is an emerging disorder affecting many people worldwide, most genetic studies ha...

Depressive symptoms

Replicated

10138

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-12

Distinguishing happiness and meaning in life from depressive symptoms: A GWAS-by-subtraction study in the UK Biobank.

de Vries LP, Demange PA et al.

Am J Med Genet B Neuropsychiatr Genet

Hedonic (happiness) and eudaimonic (meaning in life) well-being are negatively related to depressive...

Pure happiness

216479

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-07

Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population.

Humphries EM, Ahn K et al.

Mol Psychiatry

Genome-wide association studies (GWAS) of mood disorders in large case-control cohorts have identifi...

Mood disorder

1672

Participants

N/A

Studies

Details PubMed

GWAS 2022-05-09

Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects.

Howe LJ, Nivard MG et al.

Nat Genet

Estimates from genome-wide association studies (GWAS) of unrelated individuals capture effects of in...

Height (population-based)

149174

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-10

Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease.

DeMichele-Sweet MAA, Klei L et al.

Mol Psychiatry

Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent in Alzhei...

Psychosis in Alzheimer's disease

12317

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-15

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression.

Thorp JG, Campos AI et al.

Nat Hum Behav

Depression and anxiety are highly prevalent and comorbid psychiatric traits that cause considerable ...

Depression

Replicated

2079337

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-15

"The Heidelberg Five" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment.

Heilbronner U, Papiol S et al.

Am J Med Genet B Neuropsychiatr Genet

HeiDE is a longitudinal population-based study that started in the 1990s and, at baseline, assessed ...

Emotional lability

3268

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-31

Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits.

Sun D, Richard M et al.

HGG Adv

Psychological and social factors are known to influence blood pressure (BP) and risk of hypertension...

Diastolic blood pressure x depressive symptoms interaction (2df test)

Replicated

16245

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-30

Genetic basis of falling risk susceptibility in the UK Biobank Study.

Trajanoska K, Seppala LJ et al.

Commun Biol

Both extrinsic and intrinsic factors predispose older people to fall. We performed a genome-wide ass...

Falling risk

Replicated

459683

Participants

N/A

Studies

Details PubMed

GWAS 2020-07-28

Genome-wide association study and polygenic risk score analysis of esketamine treatment response.

Li QS, Wajs E et al.

Sci Rep

To elucidate the genetic underpinnings of the antidepressant efficacy of S-ketamine (esketamine) nas...

Response to esketamine in treatment resistant depression

527

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Whole exome sequencing identified six novel genes for depressive symptoms.

Li ZY, Fei CJ et al.

Mol Psychiatry

Depressive symptoms (sum-score)

2024-10-29

Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom Trajectory.

Ohseto H, Takahashi I et al.

Depress Anxiety

Perinatal depression

2024-03-15

Genome-wide association study implicates the role of TBXAS1 in the pathogenesis of depressive symptoms among the Korean population.

Park K, Do AR et al.

Transl Psychiatry

Depressive symptoms

2024-02-06

Distinguishing happiness and meaning in life from depressive symptoms: A GWAS-by-subtraction study in the UK Biobank.

de Vries LP, Demange PA et al.

Am J Med Genet B Neuropsychiatr Genet

Pure happiness

2023-07-12

Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population.

Humphries EM, Ahn K et al.

Mol Psychiatry

Mood disorder

2023-03-07

Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects.

Howe LJ, Nivard MG et al.

Nat Genet

Height (population-based)

2022-05-09

Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease.

DeMichele-Sweet MAA, Klei L et al.

Mol Psychiatry

Psychosis in Alzheimer's disease

2021-06-10

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression.

Thorp JG, Campos AI et al.

Nat Hum Behav

Depression

2021-04-15

"The Heidelberg Five" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment.

Heilbronner U, Papiol S et al.

Am J Med Genet B Neuropsychiatr Genet

Emotional lability

2021-02-15

Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits.

Sun D, Richard M et al.

HGG Adv

Diastolic blood pressure x depressive symptoms interaction (2df test)

2020-10-31

Genetic basis of falling risk susceptibility in the UK Biobank Study.

Trajanoska K, Seppala LJ et al.

Commun Biol

Falling risk

2020-09-30

Genome-wide association study and polygenic risk score analysis of esketamine treatment response.

Li QS, Wajs E et al.

Sci Rep

Response to esketamine in treatment resistant depression

2020-07-28