Active: Dupuytren's disease Clear all

GWAS 2024-01-03

A genome-wide association meta-analysis implicates Hedgehog and Notch signaling in Dupuytren's disease.

Riesmeijer SA, Kamali Z et al.

Nat Commun

Dupuytren's disease (DD) is a highly heritable fibrotic disorder of the hand with incompletely under...

Dupuytren's disease

Replicated

259315

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-01

Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals.

Ågren R, Patil S et al.

Mol Biol Evol

Dupuytren's disease is characterized by fingers becoming permanently bent in a flexed position. Wher...

Dupuytren's disease

653751

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-10

A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor.

Green HD, Jones A et al.

PLoS Genet

Frozen shoulder is a painful condition that often requires surgery and affects up to 5% of individua...

Frozen shoulder

451099

Participants

N/A

Studies

Details PubMed

GWAS 2017-09-07

A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis.

Ng M, Thakkar D et al.

Am J Hum Genet

Individuals with Dupuytren disease (DD) are commonly seen by physicians and surgeons across multiple...

Dupuytren's disease

Replicated

20849

Participants

N/A

Studies

Details PubMed

GWAS 2011-07-06

Wnt signaling and Dupuytren's disease.

Dolmans GH, Werker PM et al.

N Engl J Med

Dupuytren's disease is a benign fibromatosis of the hands and fingers that leads to flexion contract...

Dupuytren's disease

Replicated

12126

Participants

N/A

Studies

Details PubMed

GWAS 2010-10-22

Genome-wide association scan of Dupuytren's disease.

Ojwang JO, Adrianto I et al.

J Hand Surg Am

Purpose: Dupuytren's disease (DD) has a strong genetic component that is suggested by population stu...

Dupuytren's disease

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide association meta-analysis implicates Hedgehog and Notch signaling in Dupuytren's disease.

Riesmeijer SA, Kamali Z et al.

Nat Commun

Dupuytren's disease

2024-01-03

Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals.

Ågren R, Patil S et al.

Mol Biol Evol

Dupuytren's disease

2023-06-01

A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor.

Green HD, Jones A et al.

PLoS Genet

Frozen shoulder

2021-06-10

A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis.

Ng M, Thakkar D et al.

Am J Hum Genet

Dupuytren's disease

2017-09-07

Wnt signaling and Dupuytren's disease.

Dolmans GH, Werker PM et al.

N Engl J Med

Dupuytren's disease

2011-07-06

Genome-wide association scan of Dupuytren's disease.

Ojwang JO, Adrianto I et al.

J Hand Surg Am

Dupuytren's disease

2010-10-22