Menu
Currency
GWAS Study

Wnt signaling and Dupuytren's disease.

Dolmans GH, Werker PM, Hennies HC et al.

21732829 PubMed ID
GWAS Study Type
12126 Participants
236 Views
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DG
Dolmans GH
WP
Werker PM
HH
Hennies HC
FD
Furniss D
FE
Festen EA
FL
Franke L
BK
Becker K
VD
van der Vlies P
WB
Wolffenbuttel BH
TS
Tinschert S
TM
Toliat MR
NM
Nothnagel M
FA
Franke A
KN
Klopp N
WH
Wichmann HE
NP
Nürnberg P
GH
Giele H
OR
Ophoff RA
WC
Wijmenga C
Chapter II

Abstract

Summary of the research findings

Dupuytren's disease is a benign fibromatosis of the hands and fingers that leads to flexion contractures. We hypothesized that multiple genetic and environmental factors influence susceptibility to this disease and sought to identify susceptibility genes to better understand its pathogenesis.

856 European ancestry cases, 2,836 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

12126
Total Participants
GWAS
Study Type
Yes
Replicated
1,298 European ancestry cases, 7,136 European ancestry controls
Replication Participants
European
Ancestry
Netherlands, Germany, U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

AI Summary In Progress

Our AI-generated summary of this publication is being prepared. Please check back soon.