Active: Eosinophil count Clear all

GWAS 2023-08-10

Genetic relationships between high blood eosinophil count, asthma susceptibility and asthma severity.

Li H, Li X

J Asthma

Objective: Genetic relationships between blood eosinophil count (BEC), asthma susceptibility, and se...

High eosinophilic (T2) asthma vs low eosinophilic (non-T2) asthma

23443

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-03

Genome-Wide Association Study on the Hematological Phenotypic Characteristics of the Han Population from Northwest China.

Yang W, He X et al.

Pharmgenomics Pers Med

Hematological characteristics have positive reference value as clinical indicators in the evaluation...

Absolute eosinophil count

Replicated

3052

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-22

Gene-Based Variant Analysis of Whole-Exome Sequencing in Relation to Eosinophil Count.

Höglund J, Hadizadeh F et al.

Front Immunol

Eosinophils play important roles in the release of cytokine mediators in response to inflammation. M...

Eosinophil count

365954

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-02

Genome-Wide Association and Mendelian Randomization Analysis Reveal the Causal Relationship Between White Blood Cell Subtypes and Asthma in Africans.

Soremekun O, Soremekun C et al.

Front Genet

White blood cell (WBC) traits and their subtypes such as basophil count (Bas), eosinophil count (Eos...

Monocyte count

16152

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-27

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Mikhaylova AV, McHugh CP et al.

Am J Hum Genet

Many common and rare variants associated with hematologic traits have been discovered through imputa...

White blood cell count

Replicated

260928

Participants

N/A

Studies

Details PubMed

GWAS 2020-02-03

Pharmacogenetic investigation of efficacy response to mepolizumab in eosinophilic granulomatosis with polyangiitis.

Condreay LD, Parham LR et al.

Rheumatol Int

Treatment of patients with the rare disease eosinophilic granulomatosis with polyangiitis (EGPA) wit...

Frequency of relapse in mepolizumab-treated eosinophilic granulomatosis with polyangiitis

Participants

N/A

Studies

Details PubMed

GWAS 2019-11-12

Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status.

Lyons PA, Peters JE et al.

Nat Commun

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disease of unknown cause...

Eosinophilic granulomatosis with polyangiitis (MPO-ANCA positive)

Replicated

7011

Participants

N/A

Studies

Details PubMed

GWAS 2019-10-01

Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.

Gurdasani D, Carstensen T et al.

Cell

Genomic studies in African populations provide unique opportunities to understand disease etiology, ...

Eosinophil count

7526

Participants

N/A

Studies

Details PubMed

GWAS 2019-07-01

Correlation between eosinophil count, its genetic background and body mass index: The Nagahama Study.

Sunadome H, Matsumoto H et al.

Allergol Int

Obesity affects the pathogenesis of various chronic diseases, including asthma. Research on correlat...

Eosinophil count

4650

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-14

A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis.

Kristjansson RP, Benonisdottir S et al.

Nat Genet

Nasal polyps (NP) are lesions on the nasal and paranasal sinus mucosa and are a risk factor for chro...

Chronic rhinosinusitis

765694

Participants

N/A

Studies

Details PubMed

GWAS 2009-02-08

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.

Gudbjartsson DF, Bjornsdottir US et al.

Nat Genet

Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation of inf...

Eosinophil count

Replicated

26722

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic relationships between high blood eosinophil count, asthma susceptibility and asthma severity.

Li H, Li X

J Asthma

High eosinophilic (T2) asthma vs low eosinophilic (non-T2) asthma

2023-08-10

Genome-Wide Association Study on the Hematological Phenotypic Characteristics of the Han Population from Northwest China.

Yang W, He X et al.

Pharmgenomics Pers Med

Absolute eosinophil count

2022-08-03

Gene-Based Variant Analysis of Whole-Exome Sequencing in Relation to Eosinophil Count.

Höglund J, Hadizadeh F et al.

Front Immunol

Eosinophil count

2022-07-22

Genome-Wide Association and Mendelian Randomization Analysis Reveal the Causal Relationship Between White Blood Cell Subtypes and Asthma in Africans.

Soremekun O, Soremekun C et al.

Front Genet

Monocyte count

2021-12-02

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Mikhaylova AV, McHugh CP et al.

Am J Hum Genet

White blood cell count

2021-09-27

Pharmacogenetic investigation of efficacy response to mepolizumab in eosinophilic granulomatosis with polyangiitis.

Condreay LD, Parham LR et al.

Rheumatol Int

Frequency of relapse in mepolizumab-treated eosinophilic granulomatosis with polyangiitis

2020-02-03

Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status.

Lyons PA, Peters JE et al.

Nat Commun

Eosinophilic granulomatosis with polyangiitis (MPO-ANCA positive)

2019-11-12

Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.

Gurdasani D, Carstensen T et al.

Cell

Eosinophil count

2019-10-01

Correlation between eosinophil count, its genetic background and body mass index: The Nagahama Study.

Sunadome H, Matsumoto H et al.

Allergol Int

Eosinophil count

2019-07-01

A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis.

Kristjansson RP, Benonisdottir S et al.

Nat Genet

Chronic rhinosinusitis

2019-01-14

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.

Gudbjartsson DF, Bjornsdottir US et al.

Nat Genet

Eosinophil count

2009-02-08