Active: Factor VII Clear all

GWAS 2022-05-12

Whole exome sequencing of 14 389 individuals from the ESP and CHARGE consortia identifies novel rare variation associated with hemostatic factors.

Pankratz N, Wei P et al.

Hum Mol Genet

Plasma levels of fibrinogen, coagulation factors VII and VIII and von Willebrand factor (vWF) are fo...

Fibrinogen levels

13638

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-14

Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations.

Temprano-Sagrera G, Sitlani CM et al.

J Thromb Haemost

Multi-phenotype analysis of genetically correlated phenotypes can increase the statistical power to ...

Von Willebrand factor levels or factor VIII levels or tissue plasminogen activator levels (pleiotropy)

105893

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-30

Influence of ABO Locus on PFA-100 Collagen-ADP Closure Time Is Not Totally Dependent on the Von Willebrand Factor. Results of a GWAS on GAIT-2 Project Phenotypes.

Pujol-Moix N, Martinez-Perez A et al.

Int J Mol Sci

(1) Background: In a previous study, we found that two phenotypes related to platelet reactivity, me...

Platelet reactivity measurement (collagen-ADP)

935

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-14

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.

de Vries PS, Sabater-Lleal M et al.

Blood

Factor VII (FVII) is an important component of the coagulation cascade. Few genetic loci regulating ...

Factor VII activity or levels

27495

Participants

N/A

Studies

Details PubMed

GWAS 2018-11-20

Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.

Sabater-Lleal M, Huffman JE et al.

Circulation

Factor VIII (FVIII) and its carrier protein von Willebrand factor (VWF) are associated with risk of ...

Factor VIII levels

32610

Participants

N/A

Studies

Details PubMed

GWAS 2018-08-02

Genome-wide analysis of genetic determinants of circulating factor VII activating protease (FSAP) activity.

Olsson M, Stanne TM et al.

J Thromb Haemost

Essentials Knowledge of genetic regulators of plasma factor VII activating protease (FSAP) levels is...

Plasma factor VII activating protease levels

3126

Participants

N/A

Studies

Details PubMed

GWAS 2013-02-10

A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A.

Lane J, McLaren PJ et al.

Hum Mol Genet

Human genetic variation contributes to differences in susceptibility to HIV-1 infection. To search f...

HIV-1 susceptibility

1195

Participants

N/A

Studies

Details PubMed

GWAS 2011-08-02

Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.

Antoni G, Oudot-Mellakh T et al.

BMC Med Genet

Elevated levels of factor VIII (FVIII) and von Willebrand Factor (vWF) are well-established risk fac...

vWF and FVIII levels

1624

Participants

N/A

Studies

Details PubMed

GWAS 2010-03-15

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.

Smith NL, Chen MH et al.

Circulation

Plasma levels of coagulation factors VII (FVII), VIII (FVIII), and von Willebrand factor (vWF) influ...

Factor VIII levels

Replicated

22883

Participants

N/A

Studies

Details PubMed

GWAS 2007-09-19

Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.

Yang Q, Kathiresan S et al.

BMC Med Genet

Increased circulating levels of hemostatic factors as well as anemia have been associated with incre...

Factor VII

886

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Whole exome sequencing of 14 389 individuals from the ESP and CHARGE consortia identifies novel rare variation associated with hemostatic factors.

Pankratz N, Wei P et al.

Hum Mol Genet

Fibrinogen levels

2022-05-12

Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations.

Temprano-Sagrera G, Sitlani CM et al.

J Thromb Haemost

Von Willebrand factor levels or factor VIII levels or tissue plasminogen activator levels (pleiotropy)

2022-03-14

Influence of ABO Locus on PFA-100 Collagen-ADP Closure Time Is Not Totally Dependent on the Von Willebrand Factor. Results of a GWAS on GAIT-2 Project Phenotypes.

Pujol-Moix N, Martinez-Perez A et al.

Int J Mol Sci

Platelet reactivity measurement (collagen-ADP)

2019-06-30

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.

de Vries PS, Sabater-Lleal M et al.

Blood

Factor VII activity or levels

2019-01-14

Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.

Sabater-Lleal M, Huffman JE et al.

Circulation

Factor VIII levels

2018-11-20

Genome-wide analysis of genetic determinants of circulating factor VII activating protease (FSAP) activity.

Olsson M, Stanne TM et al.

J Thromb Haemost

Plasma factor VII activating protease levels

2018-08-02

A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A.

Lane J, McLaren PJ et al.

Hum Mol Genet

HIV-1 susceptibility

2013-02-10

Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.

Antoni G, Oudot-Mellakh T et al.

BMC Med Genet

vWF and FVIII levels

2011-08-02

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.

Smith NL, Chen MH et al.

Circulation

Factor VIII levels

2010-03-15

Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.

Yang Q, Kathiresan S et al.

BMC Med Genet

Factor VII

2007-09-19