Active: Fibrinogen Clear all

GWAS 2022-05-12

Whole exome sequencing of 14 389 individuals from the ESP and CHARGE consortia identifies novel rare variation associated with hemostatic factors.

Pankratz N, Wei P et al.

Hum Mol Genet

Plasma levels of fibrinogen, coagulation factors VII and VIII and von Willebrand factor (vWF) are fo...

Fibrinogen levels

13638

Participants

N/A

Studies

Details PubMed

GWAS 2017-01-20

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.

de Vries PS, Sabater-Lleal M et al.

PLoS One

An increasing number of genome-wide association (GWA) studies are now using the higher resolution 10...

Fibrinogen levels

91953

Participants

N/A

Studies

Details PubMed

GWAS 2015-11-10

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.

de Vries PS, Chasman DI et al.

Hum Mol Genet

Genome-wide association studies have previously identified 23 genetic loci associated with circulati...

Fibrinogen levels

120246

Participants

N/A

Studies

Details PubMed

GWAS 2014-12-31

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects.

Baumert J, Huang J et al.

PLoS One

Plasma fibrinogen is an acute phase protein playing an important role in the blood coagulation casca...

Fibrinogen levels (smoking status, alcohol consumption or body mass index interaction)

80607

Participants

N/A

Studies

Details PubMed

GWAS 2013-08-22

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

Sabater-Lleal M, Huang J et al.

Circulation

Estimates of the heritability of plasma fibrinogen concentration, an established predictor of cardio...

Fibrinogen

Replicated

101193

Participants

N/A

Studies

Details PubMed

GWAS 2011-07-14

Assessment of genetic determinants of the association of γ' fibrinogen in relation to cardiovascular disease.

Lovely RS, Yang Q et al.

Arterioscler Thromb Vasc Biol

Objective: γ' fibrinogen is a newly emerging biomarker that is associated with cardiovascular diseas...

Fibrinogen

3042

Participants

N/A

Studies

Details PubMed

GWAS 2010-11-18

Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.

Marzi C, Albrecht E et al.

PLoS Genet

Elevated levels of acute-phase serum amyloid A (A-SAA) cause amyloidosis and are a risk factor for a...

Amyloid A serum levels

Replicated

6348

Participants

N/A

Studies

Details PubMed

GWAS 2009-06-12

Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study.

Mälarstig A, Buil A et al.

Blood

Total plasma homocysteine concentration (tHcy) is a biomarker for atherothrombotic disease, but caus...

Homocysteine levels

Replicated

1625

Participants

N/A

Studies

Details PubMed

GWAS 2009-04-01

Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.

Dehghan A, Yang Q et al.

Circ Cardiovasc Genet

Fibrinogen is both central to blood coagulation and an acute-phase reactant. We aimed to identify co...

Fibrinogen

Replicated

39782

Participants

N/A

Studies

Details PubMed

GWAS 2009-04-01

Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.

Danik JS, Paré G et al.

Circ Cardiovasc Genet

Fibrinogen is a multifunctional circulating glycoprotein involved in wound healing, thrombosis, plat...

Fibrinogen

17686

Participants

N/A

Studies

Details PubMed

GWAS 2009-02-01

Genome-wide association study of biochemical traits in Korcula Island, Croatia.

Zemunik T, Boban M et al.

Croat Med J

Aim: To identify genetic variants underlying biochemical traits--total cholesterol, low-density lipo...

Biochemical measures

898

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Whole exome sequencing of 14 389 individuals from the ESP and CHARGE consortia identifies novel rare variation associated with hemostatic factors.

Pankratz N, Wei P et al.

Hum Mol Genet

Fibrinogen levels

2022-05-12

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.

de Vries PS, Sabater-Lleal M et al.

PLoS One

Fibrinogen levels

2017-01-20

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.

de Vries PS, Chasman DI et al.

Hum Mol Genet

Fibrinogen levels

2015-11-10

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects.

Baumert J, Huang J et al.

PLoS One

Fibrinogen levels (smoking status, alcohol consumption or body mass index interaction)

2014-12-31

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

Sabater-Lleal M, Huang J et al.

Circulation

Fibrinogen

2013-08-22

Assessment of genetic determinants of the association of γ' fibrinogen in relation to cardiovascular disease.

Lovely RS, Yang Q et al.

Arterioscler Thromb Vasc Biol

Fibrinogen

2011-07-14

Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.

Marzi C, Albrecht E et al.

PLoS Genet

Amyloid A serum levels

2010-11-18

Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study.

Mälarstig A, Buil A et al.

Blood

Homocysteine levels

2009-06-12

Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.

Dehghan A, Yang Q et al.

Circ Cardiovasc Genet

Fibrinogen

2009-04-01

Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.

Danik JS, Paré G et al.

Circ Cardiovasc Genet

Fibrinogen

2009-04-01

Genome-wide association study of biochemical traits in Korcula Island, Croatia.

Zemunik T, Boban M et al.

Croat Med J

Biochemical measures

2009-02-01