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Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.

Dehghan A, Yang Q, Peters A et al.

20031576 PubMed ID
GWAS Study Type
39782 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DA
Dehghan A
YQ
Yang Q
PA
Peters A
BS
Basu S
BJ
Bis JC
RA
Rudnicka AR
KM
Kavousi M
CM
Chen MH
BJ
Baumert J
LG
Lowe GD
MB
McKnight B
TW
Tang W
DM
de Maat M
LM
Larson MG
ES
Eyhermendy S
MW
McArdle WL
LT
Lumley T
PJ
Pankow JS
HA
Hofman A
MJ
Massaro JM
RF
Rivadeneira F
KM
Kolz M
TK
Taylor KD
VD
van Duijn CM
KS
Kathiresan S
IT
Illig T
AY
Aulchenko YS
VK
Volcik KA
JA
Johnson AD
UA
Uitterlinden AG
TG
Tofler GH
GC
Gieger C
PB
Psaty BM
CD
Couper DJ
BE
Boerwinkle E
KW
Koenig W
OC
O'Donnell CJ
WJ
Witteman JC
SD
Strachan DP
SN
Smith NL
FA
Folsom AR
Chapter II

Abstract

Summary of the research findings

Fibrinogen is both central to blood coagulation and an acute-phase reactant. We aimed to identify common variants influencing circulation fibrinogen levels.

22,096 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

39782
Total Participants
GWAS
Study Type
Yes
Replicated
17,686 European ancestry female individuals
Replication Participants
European
Ancestry
U.S., Netherlands, Germany
Recruitment Country
Chapter IV

AI-Generated Summary

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