Active: Hand Osteoarthritis Clear all

GWAS 2023-03-17

Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effect.

Styrkarsdottir U, Stefansdottir L et al.

Ann Rheum Dis

Objectives: Erosive hand osteoarthritis (EHOA) is a severe subset of hand osteoarthritis (OA). It is...

Erosive hand osteoarthritis

552164

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-03

A Functional Polymorphism Downstream of Vitamin A Regulator Gene CYP26B1 Is Associated with Hand Osteoarthritis.

Khosasih V, Liu KM et al.

Int J Mol Sci

While genetic analyses have revealed ~100 risk loci associated with osteoarthritis (OA), only eight ...

Hand Osteoarthritis

1136

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-14

Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene.

Boer CG, Yau MS et al.

Ann Rheum Dis

Despite recent advances in the understanding of the genetic architecture of osteoarthritis (OA), onl...

Hand osteoarthritis severity (hand Klsum)

Replicated

6032

Participants

N/A

Studies

Details PubMed

GWAS 2014-04-13

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

Styrkarsdottir U, Thorleifsson G et al.

Nat Genet

Osteoarthritis is the most common form of arthritis and is a major cause of pain and disability in t...

Osteoarthritis (hand, severe)

Replicated

78162

Participants

N/A

Studies

Details PubMed

GWAS 2009-06-08

A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium.

Zhai G, van Meurs JB et al.

J Med Genet

To identify the susceptibility gene in hand osteoarthritis (OA) the authors used a two-stage approac...

Osteoarthritis

Replicated

5070

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effect.

Styrkarsdottir U, Stefansdottir L et al.

Ann Rheum Dis

Erosive hand osteoarthritis

2023-03-17

A Functional Polymorphism Downstream of Vitamin A Regulator Gene CYP26B1 Is Associated with Hand Osteoarthritis.

Khosasih V, Liu KM et al.

Int J Mol Sci

Hand Osteoarthritis

2023-02-03

Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene.

Boer CG, Yau MS et al.

Ann Rheum Dis

Hand osteoarthritis severity (hand Klsum)

2020-10-14

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

Styrkarsdottir U, Thorleifsson G et al.

Nat Genet

Osteoarthritis (hand, severe)

2014-04-13

A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium.

Zhai G, van Meurs JB et al.

J Med Genet

Osteoarthritis

2009-06-08

Health & Traits Publications

Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effect.

A Functional Polymorphism Downstream of Vitamin A Regulator Gene <i>CYP26B1</i> Is Associated with Hand Osteoarthritis.

Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify <i>WNT9A</i> as novel osteoarthritis gene.

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium.