Active: Neuroblastoma Clear all

GWAS 2025-08-20

A genome-wide study on gene-nutrient interactions for hyperuricemia in a large Korean cohort (KoGES).

Kim EY, Choi JE et al.

Sci Rep

This study aimed to identify novel genetic variants associated with hyperuricemia risk across multip...

Hyperuricemia in low zinc intake

30359

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-28

Clinical significance of germline telomere length and associated genetic factors in patients with neuroblastoma.

Bae JS, Lee JW et al.

Sci Rep

Studies investigating the relationship between germline telomere length and the clinical characteris...

Germline telomere length in neuroblastoma

186

Participants

N/A

Studies

Details PubMed

GWAS 2022-02-07

Genetic analysis in African American children supports ancestry specific neuroblastoma susceptibility.

Testori A, Vaksman Z et al.

Cancer Epidemiol Biomarkers Prev

Neuroblastoma is rarer in African American (AA) children compared with American children of European...

Neuroblastoma

3619

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-12

Absolute Neutrophil Count after the First Chemotherapy Cycle as a Surrogate Marker for Treatment Outcomes in Patients with Neuroblastoma.

Lee JW, Bae JS et al.

Cancer Res Treat

Purpose: We performed this study to determine whether the degree of neutropenia after the first chem...

Absolute neutrophil count

313

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-30

Genome-Wide Association Study for the Identification of Novel Genetic Variants Associated with the Risk of Neuroblastoma in Korean Children.

Bae JS, Lee JW et al.

Cancer Res Treat

Purpose: Neuroblastoma (NB) is the most common extracranial solid tumor found in children. To identi...

Neuroblastoma (pediatric)

1296

Participants

N/A

Studies

Details PubMed

GWAS 2019-09-07

Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene.

Avitabile M, Succoio M et al.

Carcinogenesis

Neuroblastoma (NB) and malignant cutaneous melanoma (CMM) are neural crest cells (NCC)-derived tumor...

Neuroblastoma or malignant cutaneous melanoma

Replicated

48396

Participants

N/A

Studies

Details PubMed

GWAS 2018-08-09

Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease.

Gusareva ES, Twizere JC et al.

Neurobiol Aging

Systematic epistasis analyses in multifactorial disorders are an important step to better characteri...

Alzheimer's disease (SNP x SNP interaction)

Replicated

38582

Participants

N/A

Studies

Details PubMed

GWAS 2017-09-18

Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk.

Chang X, Zhao Y et al.

Nat Commun

MYCN amplification and 11q deletion are two inversely correlated prognostic factors of poor outcome ...

Neuroblastoma (11q deletion)

Replicated

7168

Participants

N/A

Studies

Details PubMed

GWAS 2017-05-18

Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma.

McDaniel LD, Conkrite KL et al.

PLoS Genet

Neuroblastoma is a cancer of the developing sympathetic nervous system that most commonly presents i...

Sporadic neuroblastoma

Replicated

11862

Participants

N/A

Studies

Details PubMed

GWAS 2012-09-02

Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma.

Diskin SJ, Capasso M et al.

Nat Genet

Neuroblastoma is a cancer of the sympathetic nervous system that accounts for approximately 10% of a...

Neuroblastoma

Replicated

10290

Participants

N/A

Studies

Details PubMed

GWAS 2011-08-16

Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations.

Wheeler HE, Gamazon ER et al.

Pharmacogenomics J

Platinating agents are used in the treatment of many cancers, yet they can induce toxicities and res...

Response to platinum-based chemotherapy (carboplatin)

608

Participants

N/A

Studies

Details PubMed

GWAS 2010-12-01

Integrative genomics identifies LMO1 as a neuroblastoma oncogene.

Wang K, Diskin SJ et al.

Nature

Neuroblastoma is a childhood cancer of the sympathetic nervous system that accounts for approximatel...

Neuroblastoma

Replicated

8348

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide study on gene-nutrient interactions for hyperuricemia in a large Korean cohort (KoGES).

Kim EY, Choi JE et al.

Sci Rep

Hyperuricemia in low zinc intake

2025-08-20

Clinical significance of germline telomere length and associated genetic factors in patients with neuroblastoma.

Bae JS, Lee JW et al.

Sci Rep

Germline telomere length in neuroblastoma

2022-07-28

Genetic analysis in African American children supports ancestry specific neuroblastoma susceptibility.

Testori A, Vaksman Z et al.

Cancer Epidemiol Biomarkers Prev

Neuroblastoma

2022-02-07

Absolute Neutrophil Count after the First Chemotherapy Cycle as a Surrogate Marker for Treatment Outcomes in Patients with Neuroblastoma.

Lee JW, Bae JS et al.

Cancer Res Treat

Absolute neutrophil count

2021-04-12

Genome-Wide Association Study for the Identification of Novel Genetic Variants Associated with the Risk of Neuroblastoma in Korean Children.

Bae JS, Lee JW et al.

Cancer Res Treat

Neuroblastoma (pediatric)

2020-06-30

Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene.

Avitabile M, Succoio M et al.

Carcinogenesis

Neuroblastoma or malignant cutaneous melanoma

2019-09-07

Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease.

Gusareva ES, Twizere JC et al.

Neurobiol Aging

Alzheimer's disease (SNP x SNP interaction)

2018-08-09

Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk.

Chang X, Zhao Y et al.

Nat Commun

Neuroblastoma (11q deletion)

2017-09-18

Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma.

McDaniel LD, Conkrite KL et al.

PLoS Genet

Sporadic neuroblastoma

2017-05-18

Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma.

Diskin SJ, Capasso M et al.

Nat Genet

Neuroblastoma

2012-09-02

Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations.

Wheeler HE, Gamazon ER et al.

Pharmacogenomics J

Response to platinum-based chemotherapy (carboplatin)

2011-08-16

Integrative genomics identifies LMO1 as a neuroblastoma oncogene.

Wang K, Diskin SJ et al.

Nature

Neuroblastoma

2010-12-01