Active: Neutrophil count Clear all

GWAS 2024-03-15

A genome-wide association study of neutrophil count in individuals associated to an African continental ancestry group facilitates studies of malaria pathogenesis.

Constantinescu AE, Hughes DA et al.

Hum Genomics

'Benign ethnic neutropenia' (BEN) is a heritable condition characterized by lower neutrophil counts,...

Neutrophil count

5976

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-17

Interplay Between Hereditary and Acquired Factors Determine Neutrophil Counts in Aging Individuals.

Gagnon MF, Provost S et al.

Blood Adv

Blood cell production is a complex process, partly genetically determined and influenced by acquired...

White blood cell count

2465

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-02

Genome-Wide Association and Mendelian Randomization Analysis Reveal the Causal Relationship Between White Blood Cell Subtypes and Asthma in Africans.

Soremekun O, Soremekun C et al.

Front Genet

White blood cell (WBC) traits and their subtypes such as basophil count (Bas), eosinophil count (Eos...

Monocyte count

16152

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-12

Absolute Neutrophil Count after the First Chemotherapy Cycle as a Surrogate Marker for Treatment Outcomes in Patients with Neuroblastoma.

Lee JW, Bae JS et al.

Cancer Res Treat

Purpose: We performed this study to determine whether the degree of neutropenia after the first chem...

Absolute neutrophil count

313

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-15

A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia.

Legge SE, Pardiñas AF et al.

Mol Psychiatry

Individuals of African ancestry in the United States and Europe are at increased risk of developing ...

Neutrophil level response to clozapine in treatment-resistant schizophrenia

552

Participants

N/A

Studies

Details PubMed

GWAS 2017-11-01

2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio.

Lin BD, Carnero-Montoro E et al.

J Hum Genet

Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are important biomarkers...

Platelet-to-lymphocyte ratio

Replicated

8439

Participants

N/A

Studies

Details PubMed

GWAS 2017-02-01

Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos.

Jain D, Hodonsky CJ et al.

Hum Mol Genet

Circulating white blood cell (WBC) counts (neutrophils, monocytes, lymphocytes, eosinophils, basophi...

White blood cell count

Replicated

19009

Participants

N/A

Studies

Details PubMed

GWAS 2014-09-30

Common variants in the CRP promoter are associated with a high C-reactive protein level in Kawasaki disease.

Kim JJ, Yun SW et al.

Pediatr Cardiol

Kawasaki disease (KD) is an acute self-limiting form of vasculitis that afflicts infants and childre...

Inflammatory biomarkers in Kawasaki disease

Replicated

651

Participants

N/A

Studies

Details PubMed

GWAS 2011-10-30

Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network.

Crosslin DR, McDavid A et al.

Hum Genet

White blood cell count (WBC) is unique among identified inflammatory predictors of chronic disease i...

White blood cell count

13533

Participants

N/A

Studies

Details PubMed

GWAS 2011-07-01

Multiple loci are associated with white blood cell phenotypes.

Nalls MA, Couper DJ et al.

PLoS Genet

White blood cell (WBC) count is a common clinical measure from complete blood count assays, and it v...

White blood cell count

Replicated

31332

Participants

N/A

Studies

Details PubMed

GWAS 2011-06-30

Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.

Okada Y, Hirota T et al.

PLoS Genet

White blood cells (WBCs) mediate immune systems and consist of various subtypes with distinct roles....

White blood cell types

Replicated

14792

Participants

N/A

Studies

Details PubMed

GWAS 2011-06-30

Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).

Reiner AP, Lettre G et al.

PLoS Genet

Total white blood cell (WBC) and neutrophil counts are lower among individuals of African descent du...

White blood cell count

Replicated

54215

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide association study of neutrophil count in individuals associated to an African continental ancestry group facilitates studies of malaria pathogenesis.

Constantinescu AE, Hughes DA et al.

Hum Genomics

Neutrophil count

2024-03-15

Interplay Between Hereditary and Acquired Factors Determine Neutrophil Counts in Aging Individuals.

Gagnon MF, Provost S et al.

Blood Adv

White blood cell count

2023-03-17

Genome-Wide Association and Mendelian Randomization Analysis Reveal the Causal Relationship Between White Blood Cell Subtypes and Asthma in Africans.

Soremekun O, Soremekun C et al.

Front Genet

Monocyte count

2021-12-02

Absolute Neutrophil Count after the First Chemotherapy Cycle as a Surrogate Marker for Treatment Outcomes in Patients with Neuroblastoma.

Lee JW, Bae JS et al.

Cancer Res Treat

Absolute neutrophil count

2021-04-12

A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia.

Legge SE, Pardiñas AF et al.

Mol Psychiatry

Neutrophil level response to clozapine in treatment-resistant schizophrenia

2019-01-15

2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio.

Lin BD, Carnero-Montoro E et al.

J Hum Genet

Platelet-to-lymphocyte ratio

2017-11-01

Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos.

Jain D, Hodonsky CJ et al.

Hum Mol Genet

White blood cell count

2017-02-01

Common variants in the CRP promoter are associated with a high C-reactive protein level in Kawasaki disease.

Kim JJ, Yun SW et al.

Pediatr Cardiol

Inflammatory biomarkers in Kawasaki disease

2014-09-30

Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network.

Crosslin DR, McDavid A et al.

Hum Genet

White blood cell count

2011-10-30

Multiple loci are associated with white blood cell phenotypes.

Nalls MA, Couper DJ et al.

PLoS Genet

White blood cell count

2011-07-01

Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.

Okada Y, Hirota T et al.

PLoS Genet

White blood cell types

2011-06-30

Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).

Reiner AP, Lettre G et al.

PLoS Genet

White blood cell count

2011-06-30