Active: PR interval Clear all

GWAS 2023-03-14

Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.

Young WJ, Haessler J et al.

Nat Commun

The 3-dimensional spatial and 2-dimensional frontal QRS-T angles are measures derived from the vecto...

Frontal QRS-T angle

159715

Participants

N/A

Studies

Details PubMed

GWAS 2020-05-21

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.

Ntalla I, Weng LC et al.

Nat Commun

The electrocardiographic PR interval reflects atrioventricular conduction, and is associated with co...

PR interval

271570

Participants

N/A

Studies

Details PubMed

GWAS 2020-05-15

Potential causal association of a prolonged PR interval and clinical recurrence of atrial fibrillation after catheter ablation: a Mendelian randomization analysis.

Hong M, Hwang I et al.

J Hum Genet

A prolonged PR interval predicts atrial fibrillation (AF) recurrence after catheter ablation. We inv...

PR interval in atrial fibrillation treated with catheter ablation

1722

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-24

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.

van Setten J, Verweij N et al.

Eur J Hum Genet

Genome-wide association studies (GWAS) of quantitative electrocardiographic (ECG) traits in large co...

PR interval

Replicated

66170

Participants

N/A

Studies

Details PubMed

GWAS 2018-07-25

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.

van Setten J, Brody JA et al.

Nat Commun

Electrocardiographic PR interval measures atrio-ventricular depolarization and conduction, and abnor...

PR interval

92340

Participants

N/A

Studies

Details PubMed

GWAS 2017-11-10

Genome-wide association study of PR interval in Hispanics/Latinos identifies novel locus at ID2.

Seyerle AA, Lin HJ et al.

Heart

Objective: PR interval (PR) is a heritable electrocardiographic measure of atrial and atrioventricul...

PR interval

Replicated

29620

Participants

N/A

Studies

Details PubMed

GWAS 2014-07-23

Genome-wide association study of electrocardiographic parameters identifies a new association for PR interval and confirms previously reported associations.

Sano M, Kamitsuji S et al.

Hum Mol Genet

Previous reports have described several associations of PR, QRS, QT and heart rate with genomic vari...

Electrocardiographic traits

Replicated

9799

Participants

N/A

Studies

Details PubMed

GWAS 2014-07-17

Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians.

Hong KW, Lim JE et al.

Hum Mol Genet

The electrocardiogram has several advantages in detecting cardiac arrhythmia-it is readily available...

PR interval

Replicated

13380

Participants

N/A

Studies

Details PubMed

GWAS 2014-06-06

A genome-wide association study to identify genomic modulators of rate control therapy in patients with atrial fibrillation.

Kolek MJ, Edwards TL et al.

Am J Cardiol

For many patients with atrial fibrillation, ventricular rate control with atrioventricular (AV) noda...

Response to rate control therapy in atrial fibrillation

Replicated

572

Participants

N/A

Studies

Details PubMed

GWAS 2014-05-21

Genetic determinants of P wave duration and PR segment.

Verweij N, Mateo Leach I et al.

Circ Cardiovasc Genet

The PR interval on the ECG reflects atrial depolarization and atrioventricular nodal delay which can...

P wave duration

16468

Participants

N/A

Studies

Details PubMed

GWAS 2013-03-28

Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans.

Jeff JM, Ritchie MD et al.

Ann Hum Genet

Electrocardiographic (ECG) measurements vary by ancestry. Genome-wide association studies (GWAS) hav...

QT interval

455

Participants

N/A

Studies

Details PubMed

GWAS 2012-11-08

Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts.

Butler AM, Yin X et al.

Circ Cardiovasc Genet

The PR interval, as measured by the resting, standard 12-lead ECG, reflects the duration of atrial/a...

PR interval

13415

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.

Young WJ, Haessler J et al.

Nat Commun

Frontal QRS-T angle

2023-03-14

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.

Ntalla I, Weng LC et al.

Nat Commun

PR interval

2020-05-21

Potential causal association of a prolonged PR interval and clinical recurrence of atrial fibrillation after catheter ablation: a Mendelian randomization analysis.

Hong M, Hwang I et al.

J Hum Genet

PR interval in atrial fibrillation treated with catheter ablation

2020-05-15

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.

van Setten J, Verweij N et al.

Eur J Hum Genet

PR interval

2019-01-24

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.

van Setten J, Brody JA et al.

Nat Commun

PR interval

2018-07-25

Genome-wide association study of PR interval in Hispanics/Latinos identifies novel locus at ID2.

Seyerle AA, Lin HJ et al.

Heart

PR interval

2017-11-10

Genome-wide association study of electrocardiographic parameters identifies a new association for PR interval and confirms previously reported associations.

Sano M, Kamitsuji S et al.

Hum Mol Genet

Electrocardiographic traits

2014-07-23

Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians.

Hong KW, Lim JE et al.

Hum Mol Genet

PR interval

2014-07-17

A genome-wide association study to identify genomic modulators of rate control therapy in patients with atrial fibrillation.

Kolek MJ, Edwards TL et al.

Am J Cardiol

Response to rate control therapy in atrial fibrillation

2014-06-06

Genetic determinants of P wave duration and PR segment.

Verweij N, Mateo Leach I et al.

Circ Cardiovasc Genet

P wave duration

2014-05-21

Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans.

Jeff JM, Ritchie MD et al.

Ann Hum Genet

QT interval

2013-03-28

Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts.

Butler AM, Yin X et al.

Circ Cardiovasc Genet

PR interval

2012-11-08