Active: Pulmonary embolism Clear all

GWAS 2024-11-06

Phenotypic and genetic characteristics of retinal vascular parameters and their association with diseases.

Ortín Vela S, Beyeler MJ et al.

Nat Commun

Fundus images allow for non-invasive assessment of the retinal vasculature whose features provide im...

Retinal venular temporal angle

57486

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-12

Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism.

Liley J, Newnham M et al.

Am J Respir Crit Care Med

Rationale: Chronic thromboembolic pulmonary hypertension involves the formation and nonresolution of...

Chronic thromboembolic pulmonary hypertension

12264

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-01

A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk.

Verdier H, Thomas P et al.

Blood

Genetic studies of platelet reactivity (PR) phenotypes may identify novel antiplatelet drug targets....

Predicted platelet reactivity

29806

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-19

Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population.

Zhang Z, Li H et al.

BMC Med

A large proportion of pulmonary embolism (PE) heritability remains unexplained, particularly among t...

Pulmonary embolism

Replicated

18934

Participants

N/A

Studies

Details PubMed

GWAS 2021-10-20

Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke.

Leskelä J, Toppila I et al.

J Am Heart Assoc

Background Translocation of lipopolysaccharide from gram-negative bacteria into the systemic circula...

Serum lipopolysaccharide activity

11296

Participants

N/A

Studies

Details PubMed

GWAS 2021-07-07

An artificial neural network approach integrating plasma proteomics and genetic data identifies PLXNA4 as a new susceptibility locus for pulmonary embolism.

Razzaq M, Iglesias MJ et al.

Sci Rep

Venous thromboembolism is the third common cardiovascular disease and is composed of two entities, d...

Venous thrombosis or pulmonary embolism

Replicated

2455

Participants

N/A

Studies

Details PubMed

GWAS 2020-07-04

A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling.

Rodriguez BAT, Bhan A et al.

Am J Hum Genet

Dual antiplatelet therapy reduces ischemic events in cardiovascular disease, but it increases bleedi...

Thrombin-induced platelet aggregation

1184

Participants

N/A

Studies

Details PubMed

GWAS 2010-07-11

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.

Gretarsdottir S, Baas AF et al.

Nat Genet

We performed a genome-wide association study on 1,292 individuals with abdominal aortic aneurysms (A...

Abdominal aortic aneurysm

Replicated

42513

Participants

N/A

Studies

Details PubMed

GWAS 2009-03-20

A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.

Takeuchi F, McGinnis R et al.

PLoS Genet

We report the first genome-wide association study (GWAS) whose sample size (1,053 Swedish subjects) ...

Warfarin maintenance dose

Replicated

1641

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Phenotypic and genetic characteristics of retinal vascular parameters and their association with diseases.

Ortín Vela S, Beyeler MJ et al.

Nat Commun

Retinal venular temporal angle

2024-11-06

Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism.

Liley J, Newnham M et al.

Am J Respir Crit Care Med

Chronic thromboembolic pulmonary hypertension

2024-03-12

A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk.

Verdier H, Thomas P et al.

Blood

Predicted platelet reactivity

2023-11-01

Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population.

Zhang Z, Li H et al.

BMC Med

Pulmonary embolism

2023-04-19

Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke.

Leskelä J, Toppila I et al.

J Am Heart Assoc

Serum lipopolysaccharide activity

2021-10-20

An artificial neural network approach integrating plasma proteomics and genetic data identifies PLXNA4 as a new susceptibility locus for pulmonary embolism.

Razzaq M, Iglesias MJ et al.

Sci Rep

Venous thrombosis or pulmonary embolism

2021-07-07

A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling.

Rodriguez BAT, Bhan A et al.

Am J Hum Genet

Thrombin-induced platelet aggregation

2020-07-04

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.

Gretarsdottir S, Baas AF et al.

Nat Genet

Abdominal aortic aneurysm

2010-07-11

A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.

Takeuchi F, McGinnis R et al.

PLoS Genet

Warfarin maintenance dose

2009-03-20