Active: Quantitative traits Clear all

GWAS 2025-05-28

Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.

Jee YH, Wang Y et al.

Nat Commun

Genome-wide association studies (GWAS) have predominantly focused on European ancestry populations, ...

White blood cell count

928679

Participants

N/A

Studies

Details PubMed

GWAS 2024-07-10

Characterising the genetic architecture of changes in adiposity during adulthood using electronic health records.

Venkatesh SS, Ganjgahi H et al.

Nat Commun

Obesity is a heritable disease, characterised by excess adiposity that is measured by body mass inde...

Change in body mass index over time

Replicated

210279

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-15

Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium.

Jiang MZ, Gaynor SM et al.

Hum Mol Genet

Inflammation biomarkers can provide valuable insight into the role of inflammatory processes in many...

CD40 levels

2381

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-01

Impact of Measurement Noise on Genetic Association Studies of Cardiac Function.

Vukadinovic M, Renjith G et al.

Pac Symp Biocomput

Recent research has effectively used quantitative traits from imaging to boost the capabilities of g...

Left ventricular ejection fraction

39624

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-16

Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits.

Chen CY, Chen TT et al.

Cell Genom

Genome-wide association studies (GWASs) have identified tens of thousands of genetic loci associated...

Hemoglobin

92615

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-28

Genome-wide association study of a semicontinuous trait: illustration of the impact of the modeling strategy through the study of Neutrophil Extracellular Traps levels.

Munsch G, Proust C et al.

NAR Genom Bioinform

Over the last years, there has been a considerable expansion of genome-wide association studies (GWA...

Plasma neutrophil extracellular trap levels

657

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-05

The genetics of a "femaleness/maleness" score in cardiometabolic traits in the UK biobank.

Vosberg DE, Pausova Z et al.

Sci Rep

We recently devised continuous "sex-scores" that sum up multiple quantitative traits, weighted by th...

Multi-trait sex score

161906

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-19

Genetic architecture of plasma Alzheimer disease biomarkers.

Bradley J, Gorijala P et al.

Hum Mol Genet

Genome-wide association studies (GWAS) of cerebrospinal fluid (CSF) Alzheimer's Disease (AD) biomark...

Plasma amyloid beta 40 levels

1964

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-13

Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder.

Mundy J, Hübel C et al.

Am J Med Genet B Neuropsychiatr Genet

The Mood Disorder Questionnaire (MDQ) is a common screening tool for bipolar disorder that assesses ...

Concurrent manic symptoms in manic depressive disorder and/or anxiety disorders (sum score)

11568

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-18

Common and rare variants associated with cardiometabolic traits across 98,622 whole-genome sequences in the All of Us research program.

Wang X, Ryu J et al.

J Hum Genet

All of Us is a biorepository aiming to advance biomedical research by providing various types of dat...

Atrial fibrillation

98564

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-03

Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes.

Lee CJ, Chen TH et al.

Commun Biol

To explore the complex genetic architecture of common diseases and traits, we conducted comprehensiv...

Kidney stones

64429

Participants

N/A

Studies

Details PubMed

GWAS 2022-09-28

Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.

Thareja G, Belkadi A et al.

Hum Mol Genet

Polygenic scores (PGS) can identify individuals at risk of adverse health events and guide genetics-...

Fibroblast growth factor 8 isoform A levels

2935

Participants

N/A

Studies

Details PubMed

Title

Author

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Disease/Trait

Date

Actions

Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.

Jee YH, Wang Y et al.

Nat Commun

White blood cell count

2025-05-28

Characterising the genetic architecture of changes in adiposity during adulthood using electronic health records.

Venkatesh SS, Ganjgahi H et al.

Nat Commun

Change in body mass index over time

2024-07-10

Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium.

Jiang MZ, Gaynor SM et al.

Hum Mol Genet

CD40 levels

2024-05-15

Impact of Measurement Noise on Genetic Association Studies of Cardiac Function.

Vukadinovic M, Renjith G et al.

Pac Symp Biocomput

Left ventricular ejection fraction

2024-01-01

Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits.

Chen CY, Chen TT et al.

Cell Genom

Hemoglobin

2023-11-16

Genome-wide association study of a semicontinuous trait: illustration of the impact of the modeling strategy through the study of Neutrophil Extracellular Traps levels.

Munsch G, Proust C et al.

NAR Genom Bioinform

Plasma neutrophil extracellular trap levels

2023-06-28

The genetics of a "femaleness/maleness" score in cardiometabolic traits in the UK biobank.

Vosberg DE, Pausova Z et al.

Sci Rep

Multi-trait sex score

2023-06-05

Genetic architecture of plasma Alzheimer disease biomarkers.

Bradley J, Gorijala P et al.

Hum Mol Genet

Plasma amyloid beta 40 levels

2023-05-19

Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder.

Mundy J, Hübel C et al.

Am J Med Genet B Neuropsychiatr Genet

Concurrent manic symptoms in manic depressive disorder and/or anxiety disorders (sum score)

2023-05-13

Common and rare variants associated with cardiometabolic traits across 98,622 whole-genome sequences in the All of Us research program.

Wang X, Ryu J et al.

J Hum Genet

Atrial fibrillation

2023-04-18

Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes.

Lee CJ, Chen TH et al.

Commun Biol

Kidney stones

2022-11-03

Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.

Thareja G, Belkadi A et al.

Hum Mol Genet

Fibroblast growth factor 8 isoform A levels

2022-09-28