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GWAS 2025-08-23

Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking.

He W, van der Most PJ et al.

Nat Commun

Strabismus is a common pediatric eye misalignment and has complex genetic and environmental causes. ...

Strabismus

975385

Participants

N/A

Studies

Details PubMed

GWAS 2019-05-09

A commonly occurring genetic variant within the NPLOC4-TSPAN10-PDE6G gene cluster is associated with the risk of strabismus.

Plotnikov D, Shah RL et al.

Hum Genet

Strabismus refers to an abnormal alignment of the eyes leading to the loss of central binocular visi...

Strabismus

Replicated

71894

Participants

N/A

Studies

Details PubMed

GWAS 2018-08-01

Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect.

Shaaban S, MacKinnon S et al.

Invest Ophthalmol Vis Sci

Purpose: To identify genetic variants conferring susceptibility to esotropia. Esotropia is the most ...

Esotropia

Replicated

7257

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking.

He W, van der Most PJ et al.

Nat Commun

Strabismus

2025-08-23

A commonly occurring genetic variant within the NPLOC4-TSPAN10-PDE6G gene cluster is associated with the risk of strabismus.

Plotnikov D, Shah RL et al.

Hum Genet

Strabismus

2019-05-09

Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect.

Shaaban S, MacKinnon S et al.

Invest Ophthalmol Vis Sci

Esotropia

2018-08-01