Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect.
Shaaban S, MacKinnon S, Andrews C et al.
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Abstract
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Purpose: To identify genetic variants conferring susceptibility to esotropia. Esotropia is the most common form of comitant strabismus, has its highest incidence in European ancestry populations, and is believed to be inherited as a complex trait.
224 European ancestry accommodative cases, 826 European ancestry non-accommodative cases, 3,740 European ancestry controls
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