Active: Suicide Clear all

GWAS 2025-11-13

Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression.

Shorter JR, Pasman JA et al.

Nat Genet

Major depressive disorder (MDD) is a common and heterogeneous disorder of complex etiology. Studying...

Early onset major depressive disorder

153532

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-15

Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder.

Bigdeli TB, Barr PB et al.

Mol Psychiatry

Persons diagnosed with schizophrenia (SCZ) or bipolar I disorder (BPI) are at high risk for self-inj...

Suicide behaviour in schizophrenia

5334

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-21

Uncommon protein-coding variants associated with suicide attempt in a diverse sample of US Army soldiers.

Wilkerson MD, Hupalo D et al.

Biol Psychiatry

Suicide is a societal and public health concern of global scale. Identifying genetic risk factors fo...

Suicide attempt

13549

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-01

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.

Docherty AR, Mullins N et al.

Am J Psychiatry

Objective: Suicidal behavior is heritable and is a major cause of death worldwide. Two large-scale g...

Suicide attempt

815178

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-14

Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.

Kimbrel NA, Ashley-Koch AE et al.

JAMA Psychiatry

Importance: Suicide is a leading cause of death; however, the molecular genetic basis of suicidal th...

Suicidal thoughts and behaviors

633778

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-17

Genome-wide association study meta-analysis of suicide death and suicidal behavior.

Li QS, Shabalin AA et al.

Mol Psychiatry

Suicide is a worldwide health crisis. We aimed to identify genetic risk variants associated with sui...

Suicide

10337

Participants

N/A

Studies

Details PubMed

GWAS 2022-06-01

Improving lithium dose prediction using population pharmacokinetics and pharmacogenomics: a cohort genome-wide association study in Sweden.

Millischer V, Matheson GJ et al.

Lancet Psychiatry

Lithium is the most effective treatment for bipolar disorder, resulting in strong suicide prevention...

Lithium clearance

2190

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-28

A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci.

Kimbrel NA, Ashley-Koch AE et al.

Mol Psychiatry

To identify pan-ancestry and ancestry-specific loci associated with attempting suicide among veteran...

Suicide attempts

Replicated

848732

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-23

Suicide Related Phenotypes in a Bipolar Sample: Genetic Underpinnings.

Lybech LKM, Calabró M et al.

Genes (Basel)

Suicide in Bipolar Disorder (BD) is a relevant clinical concern. Genetics may shape the individual r...

Suicide related phenotype (previous attempted suicide) in bipolar disorder

1174

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-09

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.

Mullins N, Kang J et al.

Biol Psychiatry

Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more f...

Suicide attempt

Replicated

959191

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-26

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.

Karlsson Linnér R, Mallard TT et al.

Nat Neurosci

Behaviors and disorders related to self-regulation, such as substance use, antisocial behavior and a...

Externalizing behaviour (multivariate analysis)

1492085

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-30

Genome-wide association study of suicidal behaviour severity in mood disorders.

Zai CC, Fabbri C et al.

World J Biol Psychiatry

Objective: Suicide is a major public health problem and it has a prominent genetic component. We per...

Suicide attempt severity in mood disorders

3506

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression.

Shorter JR, Pasman JA et al.

Nat Genet

Early onset major depressive disorder

2025-11-13

Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder.

Bigdeli TB, Barr PB et al.

Mol Psychiatry

Suicide behaviour in schizophrenia

2024-03-15

Uncommon protein-coding variants associated with suicide attempt in a diverse sample of US Army soldiers.

Wilkerson MD, Hupalo D et al.

Biol Psychiatry

Suicide attempt

2023-12-21

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.

Docherty AR, Mullins N et al.

Am J Psychiatry

Suicide attempt

2023-10-01

Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.

Kimbrel NA, Ashley-Koch AE et al.

JAMA Psychiatry

Suicidal thoughts and behaviors

2022-12-14

Genome-wide association study meta-analysis of suicide death and suicidal behavior.

Li QS, Shabalin AA et al.

Mol Psychiatry

Suicide

2022-10-17

Improving lithium dose prediction using population pharmacokinetics and pharmacogenomics: a cohort genome-wide association study in Sweden.

Millischer V, Matheson GJ et al.

Lancet Psychiatry

Lithium clearance

2022-06-01

A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci.

Kimbrel NA, Ashley-Koch AE et al.

Mol Psychiatry

Suicide attempts

2022-03-28

Suicide Related Phenotypes in a Bipolar Sample: Genetic Underpinnings.

Lybech LKM, Calabró M et al.

Genes (Basel)

Suicide related phenotype (previous attempted suicide) in bipolar disorder

2021-09-23

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.

Mullins N, Kang J et al.

Biol Psychiatry

Suicide attempt

2021-09-09

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.

Karlsson Linnér R, Mallard TT et al.

Nat Neurosci

Externalizing behaviour (multivariate analysis)

2021-08-26

Genome-wide association study of suicidal behaviour severity in mood disorders.

Zai CC, Fabbri C et al.

World J Biol Psychiatry

Suicide attempt severity in mood disorders

2021-03-30