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GWAS Study

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.

Mullins N, Kang J, Campos AI et al.

34861974 PubMed ID
GWAS Study Type
959191 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MN
Mullins N
KJ
Kang J
CA
Campos AI
CJ
Coleman JRI
EA
Edwards AC
GH
Galfalvy H
LD
Levey DF
LA
Lori A
SA
Shabalin A
SA
Starnawska A
SM
Su MH
WH
Watson HJ
AM
Adams M
AS
Awasthi S
GM
Gandal M
HJ
Hafferty JD
HA
Hishimoto A
KM
Kim M
OS
Okazaki S
OI
Otsuka I
RS
Ripke S
WE
Ware EB
BA
Bergen AW
BW
Berrettini WH
BM
Bohus M
BH
Brandt H
CX
Chang X
CW
Chen WJ
CH
Chen HC
CS
Crawford S
CS
Crow S
DE
DiBlasi E
DP
Duriez P
FF
Fernández-Aranda F
FM
Fichter MM
GS
Gallinger S
GS
Glatt SJ
GP
Gorwood P
GY
Guo Y
HH
Hakonarson H
HK
Halmi KA
HH
Hwu HG
JS
Jain S
JS
Jamain S
JS
Jiménez-Murcia S
JC
Johnson C
KA
Kaplan AS
KW
Kaye WH
KP
Keel PK
KJ
Kennedy JL
KK
Klump KL
LD
Li D
LS
Liao SC
LK
Lieb K
LL
Lilenfeld L
LC
Liu CM
MP
Magistretti PJ
MC
Marshall CR
MJ
Mitchell JE
ME
Monson ET
MR
Myers RM
PD
Pinto D
PA
Powers A
RN
Ramoz N
RS
Roepke S
RV
Rozanov V
SS
Scherer SW
SC
Schmahl C
SM
Sokolowski M
SM
Strober M
TL
Thornton LM
TJ
Treasure J
TM
Tsuang MT
WS
Witt SH
WD
Woodside DB
YZ
Yilmaz Z
ZL
Zillich L
AR
Adolfsson R
AI
Agartz I
AT
Air TM
AM
Alda M
AL
Alfredsson L
AO
Andreassen OA
AA
Anjorin A
AV
Appadurai V
SA
Soler Artigas M
VD
Van der Auwera S
AM
Azevedo MH
BN
Bass N
BC
Bau CHD
BB
Baune BT
BF
Bellivier F
BK
Berger K
BJ
Biernacka JM
BT
Bigdeli TB
BE
Binder EB
BM
Boehnke M
BM
Boks MP
BR
Bosch R
BD
Braff DL
BR
Bryant R
BM
Budde M
BE
Byrne EM
CW
Cahn W
CM
Casas M
CE
Castelao E
CJ
Cervilla JA
CB
Chaumette B
CS
Cichon S
CA
Corvin A
CN
Craddock N
CD
Craig D
DF
Degenhardt F
DS
Djurovic S
EH
Edenberg HJ
FA
Fanous AH
FJ
Foo JC
FA
Forstner AJ
FM
Frye M
FJ
Fullerton JM
GJ
Gatt JM
GP
Gejman PV
GI
Giegling I
GH
Grabe HJ
GM
Green MJ
GE
Grevet EH
GM
Grigoroiu-Serbanescu M
GB
Gutierrez B
GJ
Guzman-Parra J
HS
Hamilton SP
HM
Hamshere ML
HA
Hartmann A
HJ
Hauser J
HS
Heilmann-Heimbach S
HP
Hoffmann P
IM
Ising M
JI
Jones I
JL
Jones LA
JL
Jonsson L
KR
Kahn RS
KJ
Kelsoe JR
KK
Kendler KS
KS
Kloiber S
KK
Koenen KC
KM
Kogevinas M
KB
Konte B
KM
Krebs MO
LM
Landén M
LJ
Lawrence J
LM
Leboyer M
LP
Lee PH
LD
Levinson DF
LC
Liao C
LJ
Lissowska J
LS
Lucae S
MF
Mayoral F
MS
McElroy SL
MP
McGrath P
MP
McGuffin P
MA
McQuillin A
MS
Medland SE
MD
Mehta D
MI
Melle I
MY
Milaneschi Y
MP
Mitchell PB
ME
Molina E
MG
Morken G
MP
Mortensen PB
MB
Müller-Myhsok B
NC
Nievergelt C
NV
Nimgaonkar V
NM
Nöthen MM
OM
O'Donovan MC
OR
Ophoff RA
OM
Owen MJ
PC
Pato C
PM
Pato MT
PB
Penninx BWJH
PJ
Pimm J
PG
Pistis G
PJ
Potash JB
PR
Power RA
PM
Preisig M
QD
Quested D
RJ
Ramos-Quiroga JA
RA
Reif A
RM
Ribasés M
RV
Richarte V
RM
Rietschel M
RM
Rivera M
RA
Roberts A
RG
Roberts G
RG
Rouleau GA
RD
Rovaris DL
RD
Rujescu D
SC
Sánchez-Mora C
SA
Sanders AR
SP
Schofield PR
ST
Schulze TG
SL
Scott LJ
SA
Serretti A
SJ
Shi J
SS
Shyn SI
SL
Sirignano L
SP
Sklar P
SO
Smeland OB
SJ
Smoller JW
SE
Sonuga-Barke EJS
SG
Spalletta G
SJ
Strauss JS
ŚB
Świątkowska B
TM
Trzaskowski M
TG
Turecki G
VL
Vilar-Ribó L
VJ
Vincent JB
VH
Völzke H
WJ
Walters JTR
SW
Shannon Weickert C
WT
Weickert TW
WM
Weissman MM
WL
Williams LM
WN
Wray NR
ZC
Zai CC
AA
Ashley-Koch AE
BJ
Beckham JC
HE
Hauser ER
HM
Hauser MA
KN
Kimbrel NA
LJ
Lindquist JH
MB
McMahon B
OD
Oslin DW
QX
Qin X
AE
Agerbo E
BA
Børglum AD
BG
Breen G
EA
Erlangsen A
ET
Esko T
GJ
Gelernter J
HD
Hougaard DM
KR
Kessler RC
KH
Kranzler HR
LQ
Li QS
MN
Martin NG
MA
McIntosh AM
MO
Mors O
NM
Nordentoft M
OC
Olsen CM
PD
Porteous D
UR
Ursano RJ
WD
Wasserman D
WT
Werge T
WD
Whiteman DC
BC
Bulik CM
CH
Coon H
DD
Demontis D
DA
Docherty AR
KP
Kuo PH
LC
Lewis CM
MJ
Mann JJ
RM
Rentería ME
SD
Smith DJ
SE
Stahl EA
SM
Stein MB
SF
Streit F
WV
Willour V
RD
Ruderfer DM
Chapter II

Abstract

Summary of the research findings

Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders.

26,590 European ancestry cases, 492,022 European ancestry controls, 1,298 African American cases, 7,375 African American controls, 1,894 Asian American ancestry cases, 20,564 Asian American ancestry controls

Chapter III

Study Statistics

Key metrics and study information

959191
Total Participants
GWAS
Study Type
Yes
Replicated
14,089 European, Asian American, African American or Hispanic/Latino cases, 395,359 European, Asian American, African American or Hispanic/Latino controls
Replication Participants
European, African American or Afro-Caribbean, Asian unspecified, Asian unspecified, African American or Afro-Caribbean, European, Hispanic or Latin American
Ancestry
Canada, U.S., Ukraine, Denmark, U.K., Australia, Germany, China, Japan
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.