Active: Suicide attempt Clear all

GWAS 2025-11-13

Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression.

Shorter JR, Pasman JA et al.

Nat Genet

Major depressive disorder (MDD) is a common and heterogeneous disorder of complex etiology. Studying...

Early onset major depressive disorder

153532

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-15

Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder.

Bigdeli TB, Barr PB et al.

Mol Psychiatry

Persons diagnosed with schizophrenia (SCZ) or bipolar I disorder (BPI) are at high risk for self-inj...

Suicide behaviour in schizophrenia

5334

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-21

Uncommon protein-coding variants associated with suicide attempt in a diverse sample of US Army soldiers.

Wilkerson MD, Hupalo D et al.

Biol Psychiatry

Suicide is a societal and public health concern of global scale. Identifying genetic risk factors fo...

Suicide attempt

13549

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-01

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.

Docherty AR, Mullins N et al.

Am J Psychiatry

Objective: Suicidal behavior is heritable and is a major cause of death worldwide. Two large-scale g...

Suicide attempt

815178

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-28

A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci.

Kimbrel NA, Ashley-Koch AE et al.

Mol Psychiatry

To identify pan-ancestry and ancestry-specific loci associated with attempting suicide among veteran...

Suicide attempts

Replicated

848732

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-09

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.

Mullins N, Kang J et al.

Biol Psychiatry

Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more f...

Suicide attempt

Replicated

959191

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-30

Genome-wide association study of suicidal behaviour severity in mood disorders.

Zai CC, Fabbri C et al.

World J Biol Psychiatry

Objective: Suicide is a major public health problem and it has a prominent genetic component. We per...

Suicide attempt severity in mood disorders

3506

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-16

Genetic aetiology of self-harm ideation and behaviour.

Campos AI, Verweij KJH et al.

Sci Rep

Family studies have identified a heritable component to self-harm that is partially independent from...

Deliberate self-harm

156880

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-15

Genome-wide copy number variation-, validation- and screening study implicates a new copy number polymorphism associated with suicide attempts in major depressive disorder.

Rao S, Shi M et al.

Gene

The genetic basis of suicide attempts (SA) remains unclear. Especially the role of copy number varia...

Suicide attempts in major depressive disorder

Replicated

287

Participants

N/A

Studies

Details PubMed

GWAS 2020-05-28

Investigating evidence for a causal association between inflammation and self-harm: A multivariable Mendelian Randomisation study.

Russell AE, Ford T et al.

Brain Behav Immun

The causal role of inflammatory markers on self-harm and suicidal risk has been studied using observ...

Suicide attempts

153560

Participants

N/A

Studies

Details PubMed

GWAS 2019-10-02

Gene-level genome-wide association analysis of suicide attempt, a preliminary study in a psychiatric Mexican population.

González-Castro TB, Martínez-Magaña JJ et al.

Mol Genet Genomic Med

Evidence suggests that liability for suicide behavior is heritable; additionally, suicide has been p...

Suicide attempts

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-05

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

Mullins N, Bigdeli TB et al.

Am J Psychiatry

Objective: More than 90% of people who attempt suicide have a psychiatric diagnosis; however, twin a...

Suicide attempts in major depressive disorder

Replicated

10408

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression.

Shorter JR, Pasman JA et al.

Nat Genet

Early onset major depressive disorder

2025-11-13

Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder.

Bigdeli TB, Barr PB et al.

Mol Psychiatry

Suicide behaviour in schizophrenia

2024-03-15

Uncommon protein-coding variants associated with suicide attempt in a diverse sample of US Army soldiers.

Wilkerson MD, Hupalo D et al.

Biol Psychiatry

Suicide attempt

2023-12-21

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.

Docherty AR, Mullins N et al.

Am J Psychiatry

Suicide attempt

2023-10-01

A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci.

Kimbrel NA, Ashley-Koch AE et al.

Mol Psychiatry

Suicide attempts

2022-03-28

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.

Mullins N, Kang J et al.

Biol Psychiatry

Suicide attempt

2021-09-09

Genome-wide association study of suicidal behaviour severity in mood disorders.

Zai CC, Fabbri C et al.

World J Biol Psychiatry

Suicide attempt severity in mood disorders

2021-03-30

Genetic aetiology of self-harm ideation and behaviour.

Campos AI, Verweij KJH et al.

Sci Rep

Deliberate self-harm

2020-06-16

Genome-wide copy number variation-, validation- and screening study implicates a new copy number polymorphism associated with suicide attempts in major depressive disorder.

Rao S, Shi M et al.

Gene

Suicide attempts in major depressive disorder

2020-06-15

Investigating evidence for a causal association between inflammation and self-harm: A multivariable Mendelian Randomisation study.

Russell AE, Ford T et al.

Brain Behav Immun

Suicide attempts

2020-05-28

Gene-level genome-wide association analysis of suicide attempt, a preliminary study in a psychiatric Mexican population.

González-Castro TB, Martínez-Magaña JJ et al.

Mol Genet Genomic Med

Suicide attempts

2019-10-02

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

Mullins N, Bigdeli TB et al.

Am J Psychiatry

Suicide attempts in major depressive disorder

2019-06-05