Active: Suicide attempts Clear all

GWAS 2025-11-13

Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression.

Shorter JR, Pasman JA et al.

Nat Genet

Major depressive disorder (MDD) is a common and heterogeneous disorder of complex etiology. Studying...

Early onset major depressive disorder

153532

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-28

A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci.

Kimbrel NA, Ashley-Koch AE et al.

Mol Psychiatry

To identify pan-ancestry and ancestry-specific loci associated with attempting suicide among veteran...

Suicide attempts

Replicated

848732

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-09

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.

Mullins N, Kang J et al.

Biol Psychiatry

Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more f...

Suicide attempt

Replicated

959191

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-15

Genome-wide copy number variation-, validation- and screening study implicates a new copy number polymorphism associated with suicide attempts in major depressive disorder.

Rao S, Shi M et al.

Gene

The genetic basis of suicide attempts (SA) remains unclear. Especially the role of copy number varia...

Suicide attempts in major depressive disorder

Replicated

287

Participants

N/A

Studies

Details PubMed

GWAS 2020-05-28

Investigating evidence for a causal association between inflammation and self-harm: A multivariable Mendelian Randomisation study.

Russell AE, Ford T et al.

Brain Behav Immun

The causal role of inflammatory markers on self-harm and suicidal risk has been studied using observ...

Suicide attempts

153560

Participants

N/A

Studies

Details PubMed

GWAS 2019-10-02

Gene-level genome-wide association analysis of suicide attempt, a preliminary study in a psychiatric Mexican population.

González-Castro TB, Martínez-Magaña JJ et al.

Mol Genet Genomic Med

Evidence suggests that liability for suicide behavior is heritable; additionally, suicide has been p...

Suicide attempts

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-05

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

Mullins N, Bigdeli TB et al.

Am J Psychiatry

Objective: More than 90% of people who attempt suicide have a psychiatric diagnosis; however, twin a...

Suicide attempts in major depressive disorder

Replicated

10408

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-17

Genetic associations with suicide attempt severity and genetic overlap with major depression.

Levey DF, Polimanti R et al.

Transl Psychiatry

In 2015, ~800,000 people died by suicide worldwide. For every death by suicide there are as many as ...

Suicide attempt severity

Replicated

20153

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-04

Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide.

Ruderfer DM, Walsh CG et al.

Mol Psychiatry

Suicide accounts for nearly 800,000 deaths per year worldwide with rates of both deaths and attempts...

Suicide attempts

337199

Participants

N/A

Studies

Details PubMed

GWAS 2018-08-16

Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study.

Erlangsen A, Appadurai V et al.

Mol Psychiatry

Family studies have shown an aggregation of suicidal behavior in families. Yet, molecular studies ar...

Affective disorder and suicide attempts

17596

Participants

N/A

Studies

Details PubMed

GWAS 2018-07-17

A genome-wide association study of suicide attempts and suicidal ideation in U.S. military veterans.

Kimbrel NA, Garrett ME et al.

Psychiatry Res

Death by suicide and suicidal behavior are major concerns among U.S. military veterans; however, no ...

Suicidal ideation

1571

Participants

N/A

Studies

Details PubMed

GWAS 2017-09-13

Genomewide association studies of suicide attempts in US soldiers.

Stein MB, Ware EB et al.

Am J Med Genet B Neuropsychiatr Genet

Suicide is a global public health problem with particular resonance for the US military. Genetic ris...

Suicide attempts

Replicated

15923

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression.

Shorter JR, Pasman JA et al.

Nat Genet

Early onset major depressive disorder

2025-11-13

A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci.

Kimbrel NA, Ashley-Koch AE et al.

Mol Psychiatry

Suicide attempts

2022-03-28

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.

Mullins N, Kang J et al.

Biol Psychiatry

Suicide attempt

2021-09-09

Genome-wide copy number variation-, validation- and screening study implicates a new copy number polymorphism associated with suicide attempts in major depressive disorder.

Rao S, Shi M et al.

Gene

Suicide attempts in major depressive disorder

2020-06-15

Investigating evidence for a causal association between inflammation and self-harm: A multivariable Mendelian Randomisation study.

Russell AE, Ford T et al.

Brain Behav Immun

Suicide attempts

2020-05-28

Gene-level genome-wide association analysis of suicide attempt, a preliminary study in a psychiatric Mexican population.

González-Castro TB, Martínez-Magaña JJ et al.

Mol Genet Genomic Med

Suicide attempts

2019-10-02

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

Mullins N, Bigdeli TB et al.

Am J Psychiatry

Suicide attempts in major depressive disorder

2019-06-05

Genetic associations with suicide attempt severity and genetic overlap with major depression.

Levey DF, Polimanti R et al.

Transl Psychiatry

Suicide attempt severity

2019-01-17

Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide.

Ruderfer DM, Walsh CG et al.

Mol Psychiatry

Suicide attempts

2019-01-04

Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study.

Erlangsen A, Appadurai V et al.

Mol Psychiatry

Affective disorder and suicide attempts

2018-08-16

A genome-wide association study of suicide attempts and suicidal ideation in U.S. military veterans.

Kimbrel NA, Garrett ME et al.

Psychiatry Res

Suicidal ideation

2018-07-17

Genomewide association studies of suicide attempts in US soldiers.

Stein MB, Ware EB et al.

Am J Med Genet B Neuropsychiatr Genet

Suicide attempts

2017-09-13