Active: Systemic lupus erythematosus Clear all

GWAS 2025-10-10

Identification of genetic variants associated with lupus nephritis in a Taiwanese cohort through systematic genetic screening.

Lee JC, Hung KS et al.

Sci Rep

Lupus nephritis (LN) is a common manifestation of systemic lupus erythematosus (SLE), affecting abou...

Lupus nephritis

27592

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-09

Multiple polygenic risk scores can improve the prediction of systemic lupus erythematosus in Taiwan.

Chen YC, Liu TY et al.

Lupus Sci Med

Objective: To identify new genetic variants associated with SLE in Taiwan and establish polygenic ri...

Systemic lupus erythematosus

40808

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-08

Rare copy-number variants as modulators of common disease susceptibility.

Auwerx C, Jõeloo M et al.

Genome Med

Copy-number variations (CNVs) have been associated with rare and debilitating genomic disorders (GDs...

ICD10 M32: systemic lupus erythematosus (CNV U-shape model)

Replicated

332327

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-29

Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci.

Han X, Gharahkhani P et al.

Nat Genet

Glaucoma, a leading cause of irreversible blindness, is a highly heritable human disease. Previous g...

Primary open angle glaucoma (MTAG)

379422

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-10

Disentangling the common genetic architecture and causality of rheumatoid arthritis and systemic lupus erythematosus with COVID-19 outcomes: genome-wide cross trait analysis and bi-directional Mendelian randomization study.

Yao M, Huang X et al.

J Med Virol

Coronavirus Disease (COVID-19) may cause a dysregulation of the immune system and has complex relati...

Severe COVID-19 or rheumatoid arthritis (MTAG)

1144495

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-07

Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus.

Khunsriraksakul C, Li Q et al.

Nat Commun

Systemic lupus erythematosus is a heritable autoimmune disease that predominantly affects young wome...

Systemic lupus erythematosus (MTAG)

718496

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-18

Genetics of Osteonecrosis in Children and Adults with Systemic Lupus Erythematosus.

Webber D, Cao J et al.

Rheumatology (Oxford)

Objectives: Genetics plays an important role in SLE risk, as well as osteonecrosis (ON), a significa...

Osteonecrosis (time to event) in systemic lupus erythematosus

940

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-03

COVID-19 and systemic lupus erythematosus genetics: A balance between autoimmune disease risk and protection against infection.

Wang Y, Guga S et al.

PLoS Genet

Genome wide association studies show there is a genetic component to severe COVID-19. We find eviden...

Severe COVID-19 or systemic lupus erythematosus (inverse variance)

1371121

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-17

Genome-wide association study for systemic lupus erythematosus in an egyptian population.

Elghzaly AA, Sun C et al.

Front Genet

Systemic lupus erythematosus (SLE) susceptibility has a strong genetic component. Genome-wide associ...

Systemic lupus erythematosus

1227

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-03

Genome-wide association study of SNP- and gene-based approaches to identify susceptibility candidates for lupus nephritis in the Han Chinese population.

Song K, Zheng X et al.

Front Immunol

Lupus nephritis (LN) is one of the most common and serious complications of systemic lupus erythaema...

Lupus nephritis in systemic lupus erythematosus

Replicated

1404

Participants

N/A

Studies

Details PubMed

GWAS 2022-05-02

Genome-wide association and Mendelian randomization study of blood copper levels and 213 deep phenotypes in humans.

Yang W, Li L et al.

Commun Biol

Metal elements are present in the human body, and their levels in the blood have important impacts o...

Plasma cadmium levels

656

Participants

N/A

Studies

Details PubMed

GWAS 2022-02-12

Established risk loci for systemic lupus erythematosus at NCF2, STAT4, TNPO3, IRF5 and ITGAM associate with distinct clinical manifestations: a Danish genome-wide association study.

Leffers HCB, Westergaard D et al.

Joint Bone Spine

No abstract available Keywords: Clinical phenotype; Disease manifestations; GWAS; Genome wide associ...

Systemic lupus erythematosus

90126

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Identification of genetic variants associated with lupus nephritis in a Taiwanese cohort through systematic genetic screening.

Lee JC, Hung KS et al.

Sci Rep

Lupus nephritis

2025-10-10

Multiple polygenic risk scores can improve the prediction of systemic lupus erythematosus in Taiwan.

Chen YC, Liu TY et al.

Lupus Sci Med

Systemic lupus erythematosus

2024-05-09

Rare copy-number variants as modulators of common disease susceptibility.

Auwerx C, Jõeloo M et al.

Genome Med

ICD10 M32: systemic lupus erythematosus (CNV U-shape model)

2024-01-08

Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci.

Han X, Gharahkhani P et al.

Nat Genet

Primary open angle glaucoma (MTAG)

2023-06-29

Disentangling the common genetic architecture and causality of rheumatoid arthritis and systemic lupus erythematosus with COVID-19 outcomes: genome-wide cross trait analysis and bi-directional Mendelian randomization study.

Yao M, Huang X et al.

J Med Virol

Severe COVID-19 or rheumatoid arthritis (MTAG)

2023-02-10

Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus.

Khunsriraksakul C, Li Q et al.

Nat Commun

Systemic lupus erythematosus (MTAG)

2023-02-07

Genetics of Osteonecrosis in Children and Adults with Systemic Lupus Erythematosus.

Webber D, Cao J et al.

Rheumatology (Oxford)

Osteonecrosis (time to event) in systemic lupus erythematosus

2023-01-18

COVID-19 and systemic lupus erythematosus genetics: A balance between autoimmune disease risk and protection against infection.

Wang Y, Guga S et al.

PLoS Genet

Severe COVID-19 or systemic lupus erythematosus (inverse variance)

2022-11-03

Genome-wide association study for systemic lupus erythematosus in an egyptian population.

Elghzaly AA, Sun C et al.

Front Genet

Systemic lupus erythematosus

2022-10-17

Genome-wide association study of SNP- and gene-based approaches to identify susceptibility candidates for lupus nephritis in the Han Chinese population.

Song K, Zheng X et al.

Front Immunol

Lupus nephritis in systemic lupus erythematosus

2022-10-03

Genome-wide association and Mendelian randomization study of blood copper levels and 213 deep phenotypes in humans.

Yang W, Li L et al.

Commun Biol

Plasma cadmium levels

2022-05-02

Established risk loci for systemic lupus erythematosus at NCF2, STAT4, TNPO3, IRF5 and ITGAM associate with distinct clinical manifestations: a Danish genome-wide association study.

Leffers HCB, Westergaard D et al.

Joint Bone Spine

Systemic lupus erythematosus

2022-02-12