Genetics of Osteonecrosis in Children and Adults with Systemic Lupus Erythematosus.
Webber D, Cao J, Dominguez D et al.
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Objectives: Genetics plays an important role in SLE risk, as well as osteonecrosis (ON), a significant and often debilitating complication of SLE. We aimed to identify genetic risk loci for ON in people with childhood-onset (cSLE) and adult-onset (aSLE) SLE.
305 European ancestry individuals, 240 East Asian ancestry individuals, 123 African ancestry individuals, 89 South Asian ancestry individuals, 25 Amerindian ancestry individuals, 158 admixed ancestry individuals
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