Active: sarcopenia Clear all

GWAS 2024-05-20

A genome-wide association study identifies a locus associated with knee extension strength in older Japanese individuals.

Ito S, Takuwa H et al.

Commun Biol

Sarcopenia is a common skeletal muscle disease in older people. Lower limb muscle strength is a good...

Knee extension strength

3452

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-01

Gene polymorphisms associated with heterogeneity and senescence characteristics of sarcopenia in chronic obstructive pulmonary disease.

Attaway AH, Bellar A et al.

J Cachexia Sarcopenia Muscle

Sarcopenia, or loss of skeletal muscle mass and decreased contractile strength, contributes to morbi...

Sarcopenia in chronic obstructive pulmonary disease (fat-free mass index defined)

Replicated

32426

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-26

Demographic and Genome Wide Association Analyses According to Muscle Mass Using Data of the Korean Genome and Epidemiology Study.

Gim JA, Lee S et al.

J Korean Med Sci

Sarcopenia is commonly found in the elderly due to a decline in muscle mass. Many researchers have p...

sarcopenia

389

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-03

Unveiling genetic variants for age-related sarcopenia by conducting a genome-wide association study on Korean cohorts.

Jin H, Yoo HJ et al.

Sci Rep

Sarcopenia is an age-related disorder characterised by a progressive decrease in skeletal muscle mas...

Body fat mass

6961

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-16

A Genome-Wide Association Study Identifies Novel Risk Loci for Sarcopenia in a Taiwanese Population.

Wu SE, Chen WL

J Inflamm Res

Purpose: A genome-wide association study (GWAS) of sarcopenia unraveled the importance of genetic co...

Low skeletal muscle mass index

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-09

Association between polygenetic risk scores related to sarcopenia risk and their interactions with regular exercise in a large cohort of Korean adults.

Park S

Clin Nutr

Background & aims: Sarcopenia elevates metabolic disorders in the elderly, and genetic and envir...

sarcopenia

17110

Participants

N/A

Studies

Details PubMed

GWAS 2021-01-28

Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.

Jones G, Trajanoska K et al.

Nat Commun

Low muscle strength is an important heritable indicator of poor health linked to morbidity and morta...

Low hand grip strength (60 years and older) (EWGSOP)

256523

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-23

The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study.

Pei YF, Liu YZ et al.

Commun Biol

Appendicular lean mass (ALM) is a heritable trait associated with loss of lean muscle mass and stren...

Appendicular lean mass

450243

Participants

N/A

Studies

Details PubMed

GWAS 2020-03-19

Replication of FTO Gene associated with lean mass in a Meta-Analysis of Genome-Wide Association Studies.

Ran S, Jiang ZX et al.

Sci Rep

Sarcopenia is characterized by low skeletal muscle, a complex trait with high heritability. With the...

Lean mass index

Replicated

46503

Participants

N/A

Studies

Details PubMed

GWAS 2020-03-09

Association of 3p27.1 Variants with Whole Body Lean Mass Identified by a Genome-wide Association Study.

Ran S, Zhang YX et al.

Sci Rep

Whole body lean mass (WBLM) is a heritable trait predicting sarcopenia. To identify genomic locus un...

Lean body mass

Replicated

8211

Participants

N/A

Studies

Details PubMed

GWAS 2015-04-22

Genomics and metabolomics of muscular mass in a community-based sample of UK females.

Korostishevsky M, Steves CJ et al.

Eur J Hum Genet

The contribution of specific molecular-genetic factors to muscle mass variation and sarcopenia remai...

Blood metabolite levels

3953

Participants

N/A

Studies

Details PubMed

GWAS 2014-05-23

Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5'-flanking region of PRDM16 gene associated with lean body mass.

Urano T, Shiraki M et al.

Aging Cell

Genetic factors are important for the development of sarcopenia, a geriatric disorder characterized ...

Lean body mass

Replicated

1350

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide association study identifies a locus associated with knee extension strength in older Japanese individuals.

Ito S, Takuwa H et al.

Commun Biol

Knee extension strength

2024-05-20

Gene polymorphisms associated with heterogeneity and senescence characteristics of sarcopenia in chronic obstructive pulmonary disease.

Attaway AH, Bellar A et al.

J Cachexia Sarcopenia Muscle

Sarcopenia in chronic obstructive pulmonary disease (fat-free mass index defined)

2023-03-01

Demographic and Genome Wide Association Analyses According to Muscle Mass Using Data of the Korean Genome and Epidemiology Study.

Gim JA, Lee S et al.

J Korean Med Sci

sarcopenia

2022-12-26

Unveiling genetic variants for age-related sarcopenia by conducting a genome-wide association study on Korean cohorts.

Jin H, Yoo HJ et al.

Sci Rep

Body fat mass

2022-03-03

A Genome-Wide Association Study Identifies Novel Risk Loci for Sarcopenia in a Taiwanese Population.

Wu SE, Chen WL

J Inflamm Res

Low skeletal muscle mass index

2021-11-16

Association between polygenetic risk scores related to sarcopenia risk and their interactions with regular exercise in a large cohort of Korean adults.

Park S

Clin Nutr

sarcopenia

2021-09-09

Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.

Jones G, Trajanoska K et al.

Nat Commun

Low hand grip strength (60 years and older) (EWGSOP)

2021-01-28

The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study.

Pei YF, Liu YZ et al.

Commun Biol

Appendicular lean mass

2020-10-23

Replication of FTO Gene associated with lean mass in a Meta-Analysis of Genome-Wide Association Studies.

Ran S, Jiang ZX et al.

Sci Rep

Lean mass index

2020-03-19

Association of 3p27.1 Variants with Whole Body Lean Mass Identified by a Genome-wide Association Study.

Ran S, Zhang YX et al.

Sci Rep

Lean body mass

2020-03-09

Genomics and metabolomics of muscular mass in a community-based sample of UK females.

Korostishevsky M, Steves CJ et al.

Eur J Hum Genet

Blood metabolite levels

2015-04-22

Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5'-flanking region of PRDM16 gene associated with lean body mass.

Urano T, Shiraki M et al.

Aging Cell

Lean body mass

2014-05-23