Active: BMC Med Genomics Clear all

GWAS 2024-04-29

Genome-wide association study and trans-ethnic meta-analysis identify novel susceptibility loci for type 2 diabetes mellitus.

Elashi AA, Toor SM et al.

BMC Med Genomics

The genetic basis of type 2 diabetes (T2D) is under-investigated in the Middle East, despite the rap...

Type 2 diabetes

11436

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-02

Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records.

Ruth KS, Beaumont RN et al.

BMC Med Genomics

Vasomotor symptoms (VMS) can often significantly impact women's quality of life at menopause. In viv...

Menopausal vasomotor symptoms

92028

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-25

New susceptibility alleles associated with severe coronary artery stenosis in the Lebanese population.

Wakim V, Abi Khalil E et al.

BMC Med Genomics

Coronary Artery Disease (CAD) is the narrowing or blockage of the coronary arteries. It is closely a...

Severe coronary stenosis (family history of CAD interaction)

2491

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-18

Genome-wide association study identifies new loci associated with risk of HBV infection and disease progression.

Zeng Z, Liu H et al.

BMC Med Genomics

Recent studies have identified susceptibility genes of HBV clearance, chronic hepatitis B, liver cir...

Persistent hepatitis B virus infection

862

Participants

N/A

Studies

Details PubMed

GWAS 2021-01-11

Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia.

Ustinova M, Peculis R et al.

BMC Med Genomics

Type 2 diabetes complications cause a serious emotional and economical burden to patients and health...

Diabetic neuropathy in type 2 diabetes

600

Participants

N/A

Studies

Details PubMed

GWAS 2021-01-06

Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test.

Jonsson A, Stinson SE et al.

BMC Med Genomics

In order to explore the pathophysiology underlying type 2 diabetes we examined the impact of gene va...

Glucagon levels in response to oral glucose tolerance test (decremental area under the curve for 0-30 minutes)

1899

Participants

N/A

Studies

Details PubMed

GWAS 2020-08-26

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease.

Winkler TW, Grassmann F et al.

BMC Med Genomics

Advanced age-related macular degeneration (AMD) is a leading cause of blindness. While around half o...

Early age-related macular degeneration

105248

Participants

N/A

Studies

Details PubMed

GWAS 2019-12-30

Region-based interaction detection in genome-wide case-control studies.

Zhang S, Jiang W et al.

BMC Med Genomics

In genome-wide association study (GWAS), conventional interaction detection methods such as BOOST ar...

Renal complication in type 2 diabetes

3113

Participants

N/A

Studies

Details PubMed

GWAS 2019-12-19

Genome-wide association study in Chinese cohort identifies one novel hypospadias risk associated locus at 12q13.13.

Chen Z, Lin X et al.

BMC Med Genomics

Hypospadias risk-associated gene variants have been reported in populations of European descent usin...

Hypospadias (moderate to severe)

Replicated

1958

Participants

N/A

Studies

Details PubMed

GWAS 2019-08-19

Genome-wide association study identifies new susceptible loci of IgA nephropathy in Koreans.

Jeong KH, Kim JS et al.

BMC Med Genomics

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Recent ...

IgA nephropathy

Replicated

1391

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-14

Local genetic ancestry in CDKN2B-AS1 is associated with primary open-angle glaucoma in an African American cohort extracted from de-identified electronic health records.

Restrepo NA, Laper SM et al.

BMC Med Genomics

Glaucoma is a leading cause of blindness in developed countries. Primary open-angle glaucoma (POAG),...

Glaucoma (primary open-angle)

1514

Participants

N/A

Studies

Details PubMed

GWAS 2018-05-10

Genome-wide association study identifies two loci influencing plasma neurofilament light levels.

Li JQ, Yuan XZ et al.

BMC Med Genomics

Plasma neurofilament light (NFL) is a promising biomarker for Alzheimer disease (AD), which increase...

Plasma neurofilament light levels

527

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association study and trans-ethnic meta-analysis identify novel susceptibility loci for type 2 diabetes mellitus.

Elashi AA, Toor SM et al.

BMC Med Genomics

Type 2 diabetes

2024-04-29

Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records.

Ruth KS, Beaumont RN et al.

BMC Med Genomics

Menopausal vasomotor symptoms

2023-10-02

New susceptibility alleles associated with severe coronary artery stenosis in the Lebanese population.

Wakim V, Abi Khalil E et al.

BMC Med Genomics

Severe coronary stenosis (family history of CAD interaction)

2021-03-25

Genome-wide association study identifies new loci associated with risk of HBV infection and disease progression.

Zeng Z, Liu H et al.

BMC Med Genomics

Persistent hepatitis B virus infection

2021-03-18

Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia.

Ustinova M, Peculis R et al.

BMC Med Genomics

Diabetic neuropathy in type 2 diabetes

2021-01-11

Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test.

Jonsson A, Stinson SE et al.

BMC Med Genomics

Glucagon levels in response to oral glucose tolerance test (decremental area under the curve for 0-30 minutes)

2021-01-06

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease.

Winkler TW, Grassmann F et al.

BMC Med Genomics

Early age-related macular degeneration

2020-08-26

Region-based interaction detection in genome-wide case-control studies.

Zhang S, Jiang W et al.

BMC Med Genomics

Renal complication in type 2 diabetes

2019-12-30

Genome-wide association study in Chinese cohort identifies one novel hypospadias risk associated locus at 12q13.13.

Chen Z, Lin X et al.

BMC Med Genomics

Hypospadias (moderate to severe)

2019-12-19

Genome-wide association study identifies new susceptible loci of IgA nephropathy in Koreans.

Jeong KH, Kim JS et al.

BMC Med Genomics

IgA nephropathy

2019-08-19

Local genetic ancestry in CDKN2B-AS1 is associated with primary open-angle glaucoma in an African American cohort extracted from de-identified electronic health records.

Restrepo NA, Laper SM et al.

BMC Med Genomics

Glaucoma (primary open-angle)

2018-09-14

Genome-wide association study identifies two loci influencing plasma neurofilament light levels.

Li JQ, Yuan XZ et al.

BMC Med Genomics

Plasma neurofilament light levels

2018-05-10