Active: Blood Clear all

GWAS 2026-01-29

Common variation at 1q23.3, 2p23.3, 2q33.3, and 2p21 influences risk of acute myeloid leukemia.

Ranasinghe D

Blood

Acute myeloid leukemia (all cytogenetic sub-types)

17648

Participants

N/A

Studies

Details PubMed

GWAS 2025-11-01

Molecular determinants of thrombosis recurrence risk across venous thromboembolism subtypes.

Munsch G

Blood

Venous thromboembolism recurrence in VTE

6355

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-13

A Multi-Omics Approach Reveals Novel Regulators of Plasma Factor V Levels: highlight on CLEC4M as a Clearance Receptor.

Munsch G, Mohapatra AK et al.

Blood

Coagulation factor V (FV) is a key protein in maintaining the hemostatic balance, with abnormal plas...

Coagulation Factor V levels

4373

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-08

Genetic Basis of Altered Platelet Counts and Gestational Thrombocytopenia in Pregnancy.

Yang Z, Hu L et al.

Blood

Platelet count reduction occurs throughout pregnancy, with 5% to 12% of pregnant women being diagnos...

Platelet count during second trimester of pregnancy

72816

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-01

A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk.

Verdier H, Thomas P et al.

Blood

Genetic studies of platelet reactivity (PR) phenotypes may identify novel antiplatelet drug targets....

Predicted platelet reactivity

29806

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-04

ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia.

Karnes JH, Rollin J et al.

Blood

Heparin-induced thrombocytopenia (HIT) is an unpredictable, potentially catastrophic adverse effect ...

Heparin-induced thrombocytopenia in PF4/heparin antibody positivity

2780

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-10

Genome-wide association study on 13,167 individuals identifies regulators of blood CD34+ cell levels.

Lopez de Lapuente Portilla A, Ekdahl L et al.

Blood

Stem cell transplantation is a cornerstone in the treatment of blood malignancies. The most common m...

Peripheral blood CD34+ cell levels

Replicated

13167

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-02

Elevated plasma concentration of complement factor C5 is associated with risk of future venous thromboembolism.

Skjeflo EW, Brækkan SK et al.

Blood

The role of complement in the pathogenesis of venous thromboembolism (VTE) is unclear. We wanted to ...

Complement C5 levels

709

Participants

N/A

Studies

Details PubMed

GWAS 2021-07-16

Genetic Variants Associated with Cytomegalovirus Infection after Allogeneic Hematopoietic Cell Transplantation.

Casto AM, Seo S et al.

Blood

Human cytomegalovirus (CMV) reactivation is a frequent complication of allogeneic hematopoietic cell...

Cytomegalovirus reactivation after allogeneic hematopoietic cell transplantation (recipients)

Replicated

2169

Participants

N/A

Studies

Details PubMed

GWAS 2020-08-19

Germline Genetic Factors Influence Outcome of Interferon Alpha Therapy in Polycythemia Vera.

Jäger R, Gisslinger H et al.

Blood

Interferon-α (IFN-α)-based treatments can induce hematologic and molecular responses (HRs and MRs, r...

response to ropeginterferon alfa-2b in polycythemia vera

Replicated

149

Participants

N/A

Studies

Details PubMed

GWAS 2019-08-16

Genomic and Transcriptomic Association Studies Identify 16 Novel Susceptibility Loci for Venous Thromboembolism.

Lindström S, Wang L et al.

Blood

Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality. To advance our...

Venous thromboembolism

187204

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-14

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.

de Vries PS, Sabater-Lleal M et al.

Blood

Factor VII (FVII) is an important component of the coagulation cascade. Few genetic loci regulating ...

Factor VII activity or levels

27495

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Common variation at 1q23.3, 2p23.3, 2q33.3, and 2p21 influences risk of acute myeloid leukemia.

Ranasinghe D

Blood

Acute myeloid leukemia (all cytogenetic sub-types)

2026-01-29

Molecular determinants of thrombosis recurrence risk across venous thromboembolism subtypes.

Munsch G

Blood

Venous thromboembolism recurrence in VTE

2025-11-01

A Multi-Omics Approach Reveals Novel Regulators of Plasma Factor V Levels: highlight on CLEC4M as a Clearance Receptor.

Munsch G, Mohapatra AK et al.

Blood

Coagulation Factor V levels

2025-05-13

Genetic Basis of Altered Platelet Counts and Gestational Thrombocytopenia in Pregnancy.

Yang Z, Hu L et al.

Blood

Platelet count during second trimester of pregnancy

2023-12-08

A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk.

Verdier H, Thomas P et al.

Blood

Predicted platelet reactivity

2023-11-01

ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia.

Karnes JH, Rollin J et al.

Blood

Heparin-induced thrombocytopenia in PF4/heparin antibody positivity

2022-03-04

Genome-wide association study on 13,167 individuals identifies regulators of blood CD34+ cell levels.

Lopez de Lapuente Portilla A, Ekdahl L et al.

Blood

Peripheral blood CD34+ cell levels

2022-01-10

Elevated plasma concentration of complement factor C5 is associated with risk of future venous thromboembolism.

Skjeflo EW, Brækkan SK et al.

Blood

Complement C5 levels

2021-08-02

Genetic Variants Associated with Cytomegalovirus Infection after Allogeneic Hematopoietic Cell Transplantation.

Casto AM, Seo S et al.

Blood

Cytomegalovirus reactivation after allogeneic hematopoietic cell transplantation (recipients)

2021-07-16

Germline Genetic Factors Influence Outcome of Interferon Alpha Therapy in Polycythemia Vera.

Jäger R, Gisslinger H et al.

Blood

response to ropeginterferon alfa-2b in polycythemia vera

2020-08-19

Genomic and Transcriptomic Association Studies Identify 16 Novel Susceptibility Loci for Venous Thromboembolism.

Lindström S, Wang L et al.

Blood

Venous thromboembolism

2019-08-16

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.

de Vries PS, Sabater-Lleal M et al.

Blood

Factor VII activity or levels

2019-01-14