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GWAS 2025-05-16

A Spanish-Portuguese GWAS of progressive supranuclear palsy reveals a novel risk locus in NFASC.

García-González P, Rodrigo Lara H et al.

Eur J Hum Genet

Progressive supranuclear palsy (PSP) is a rare 4-repeat tauopathy that causes behavioural, movement ...

Progressive supranuclear palsy

3909

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-10

Genome, HLA and polygenic risk score analyses for prevalent and persistent cervical human papillomavirus (HPV) infections.

Adebamowo SN, Adeyemo A et al.

Eur J Hum Genet

Genetic variants that underlie susceptibility to cervical high-risk human papillomavirus (hrHPV) inf...

Cervical high-risk human papilloma virus infection

Replicated

10749

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-20

A genome-wide association analysis of loss of ambulation in dystrophinopathy patients suggests multiple candidate modifiers of disease severity.

Flanigan KM, Waldrop MA et al.

Eur J Hum Genet

The major determinant of disease severity in Duchenne muscular dystrophy (DMD) or milder Becker musc...

Loss of ambulation in Duchenne muscular dystrophy

419

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-16

Genome-wide meta-analysis identifies novel loci conferring risk of acne vulgaris.

Teder-Laving M, Kals M et al.

Eur J Hum Genet

Acne vulgaris is a common chronic skin disorder presenting with comedones, cystic structures forming...

acne vulgaris

399413

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-15

Rare-variant association analysis reveals known and new age-related hearing loss genes.

Cornejo-Sanchez DM, Li G et al.

Eur J Hum Genet

Age-related (AR) hearing loss (HL) is a prevalent sensory deficit in the elderly population. Several...

Hearing difficulty

107507

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-29

Examination of a novel expression-based gene-SNP annotation strategy to identify tissue-specific contributions to heritability in multiple traits.

Mize TJ, Evans LM

Eur J Hum Genet

Complex traits show clear patterns of tissue-specific expression influenced by single nucleotide pol...

Inflammatory bowel disease

335453

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-16

Genome-wide association study of a lipedema phenotype among women in the UK Biobank identifies multiple genetic risk factors.

Klimentidis YC, Chen Z et al.

Eur J Hum Genet

Lipedema is a common disorder characterized by excessive deposition of subcutaneous adipose tissue (...

Lipedema

Replicated

195655

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-14

Polygenic risk modeling for prediction of epithelial ovarian cancer risk.

Dareng EO, Tyrer JP et al.

Eur J Hum Genet

Polygenic risk scores (PRS) for epithelial ovarian cancer (EOC) have the potential to improve risk s...

Non-mucinous epithelial ovarian cancer

63702

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-26

Identification of novel locus associated with coronary artery aneurysms and validation of loci for susceptibility to Kawasaki disease.

Hoggart C, Shimizu C et al.

Eur J Hum Genet

Kawasaki disease (KD) is a paediatric vasculitis associated with coronary artery aneurysms (CAA). Ge...

Kawasaki disease

Replicated

8456

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-27

An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease.

Ruotsalainen SE, Partanen JJ et al.

Eur J Hum Genet

Multivariate methods are known to increase the statistical power to detect associations in the case ...

Inflammatory biomarkers (multivariate analysis)

6890

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-22

Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis.

Wei XT, Feng GJ et al.

Eur J Hum Genet

Osteoporosis and obesity are two severe complex diseases threatening public health worldwide. Both d...

Bone mineral density (hip)

12981

Participants

N/A

Studies

Details PubMed

GWAS 2020-05-13

The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic.

COVID-19 Host Genetics Initiative

Eur J Hum Genet

No abstract available

COVID-19 (hospitalized vs population) RELEASE 4

969716

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A Spanish-Portuguese GWAS of progressive supranuclear palsy reveals a novel risk locus in NFASC.

García-González P, Rodrigo Lara H et al.

Eur J Hum Genet

Progressive supranuclear palsy

2025-05-16

Genome, HLA and polygenic risk score analyses for prevalent and persistent cervical human papillomavirus (HPV) infections.

Adebamowo SN, Adeyemo A et al.

Eur J Hum Genet

Cervical high-risk human papilloma virus infection

2024-01-10

A genome-wide association analysis of loss of ambulation in dystrophinopathy patients suggests multiple candidate modifiers of disease severity.

Flanigan KM, Waldrop MA et al.

Eur J Hum Genet

Loss of ambulation in Duchenne muscular dystrophy

2023-03-20

Genome-wide meta-analysis identifies novel loci conferring risk of acne vulgaris.

Teder-Laving M, Kals M et al.

Eur J Hum Genet

acne vulgaris

2023-03-16

Rare-variant association analysis reveals known and new age-related hearing loss genes.

Cornejo-Sanchez DM, Li G et al.

Eur J Hum Genet

Hearing difficulty

2023-02-15

Examination of a novel expression-based gene-SNP annotation strategy to identify tissue-specific contributions to heritability in multiple traits.

Mize TJ, Evans LM

Eur J Hum Genet

Inflammatory bowel disease

2022-11-29

Genome-wide association study of a lipedema phenotype among women in the UK Biobank identifies multiple genetic risk factors.

Klimentidis YC, Chen Z et al.

Eur J Hum Genet

Lipedema

2022-11-16

Polygenic risk modeling for prediction of epithelial ovarian cancer risk.

Dareng EO, Tyrer JP et al.

Eur J Hum Genet

Non-mucinous epithelial ovarian cancer

2022-01-14

Identification of novel locus associated with coronary artery aneurysms and validation of loci for susceptibility to Kawasaki disease.

Hoggart C, Shimizu C et al.

Eur J Hum Genet

Kawasaki disease

2021-03-26

An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease.

Ruotsalainen SE, Partanen JJ et al.

Eur J Hum Genet

Inflammatory biomarkers (multivariate analysis)

2020-10-27

Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis.

Wei XT, Feng GJ et al.

Eur J Hum Genet

Bone mineral density (hip)

2020-09-22

The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic.

COVID-19 Host Genetics Initiative

Eur J Hum Genet

COVID-19 (hospitalized vs population) RELEASE 4

2020-05-13