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GWAS 2020-04-14

Association of germline genetic variants with <i>TMPRSS2-ERG</i> fusion status in prostate cancer.

Kohaar I, Li Q et al.

Oncotarget

Introduction: Oncogenic activation of ERG resulting from TMPRSS2-ERG gene fusion is a key molecular ...

Prostate cancer

321

Participants

N/A

Studies

Details PubMed

GWAS 2017-11-28

Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer.

Khan S, Fagerholm R et al.

Oncotarget

The majority of breast cancers are driven by the female hormone oestrogen via oestrogen receptor (ER...

Survival in breast cancer (estrogen-receptor positive)

3136

Participants

N/A

Studies

Details PubMed

GWAS 2017-11-25

Cancer risk susceptibility loci in a Swedish population.

Liu W, Jiao X et al.

Oncotarget

A germline mutation in cancer predisposing genes is known to increase the risk of more than one tumo...

Cancer

19136

Participants

N/A

Studies

Details PubMed

GWAS 2017-10-09

Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

Hofer P, Hagmann M et al.

Oncotarget

Most genome-wide association studies (GWAS) were analyzed using single marker tests in combination w...

Colorectal cancer

2469

Participants

N/A

Studies

Details PubMed

GWAS 2017-09-16

Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population.

Lin E, Kuo PH et al.

Oncotarget

Although the association of single nucleotide polymorphisms (SNPs) with metabolic syndrome (MetS) ha...

Metabolic syndrome

10300

Participants

N/A

Studies

Details PubMed

GWAS 2017-08-24

A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic pulmonary arterial hypertension in a Japanese population.

Kimura M, Tamura Y et al.

Oncotarget

Pulmonary arterial hypertension (PAH) is a lethal disease that often affects the young. Although Bon...

Pulmonary arterial hypertension

Replicated

3037

Participants

N/A

Studies

Details PubMed

GWAS 2017-03-18

Genome-wide association study of high-altitude pulmonary edema in a Han Chinese population.

Li X, Jin T et al.

Oncotarget

A two-stage genome-wide association study (GWAS) was performed to identify and analyze genes and sin...

High-altitude pulmonary edema

Replicated

655

Participants

N/A

Studies

Details PubMed

GWAS 2017-03-14

TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer.

Fagerholm R, Khan S et al.

Oncotarget

TP53 overexpression is indicative of somatic TP53 mutations and associates with aggressive tumors an...

Survival in breast cancer (TP53 expression interaction)

Replicated

5182

Participants

N/A

Studies

Details PubMed

GWAS 2017-02-09

Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.

Ransohoff KJ, Wu W et al.

Oncotarget

Genome-wide association studies have identified 21 susceptibility loci associated with melanoma. The...

Melanoma

Replicated

294237

Participants

N/A

Studies

Details PubMed

GWAS 2017-01-31

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

Lv H, Zhang M et al.

Oncotarget

Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, and generally considere...

Core binding factor acute myeloid leukemia

393

Participants

N/A

Studies

Details PubMed

GWAS 2016-10-14

GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients.

Cox DG, Curtit E et al.

Oncotarget

Genetic polymorphisms are associated with breast cancer risk. Clinical and epidemiological observati...

Estrogen receptor status in HER2 positive breast cancer

3275

Participants

N/A

Studies

Details PubMed

GWAS 2016-08-01

Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21.

Zhang M, Wang Z et al.

Oncotarget

Genome-wide association studies (GWAS) have identified common pancreatic cancer susceptibility varia...

Pancreatic cancer

Replicated

27583

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Association of germline genetic variants with <i>TMPRSS2-ERG</i> fusion status in prostate cancer.

Kohaar I, Li Q et al.

Oncotarget

Prostate cancer

2020-04-14

Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer.

Khan S, Fagerholm R et al.

Oncotarget

Survival in breast cancer (estrogen-receptor positive)

2017-11-28

Cancer risk susceptibility loci in a Swedish population.

Liu W, Jiao X et al.

Oncotarget

Cancer

2017-11-25

Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

Hofer P, Hagmann M et al.

Oncotarget

Colorectal cancer

2017-10-09

Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population.

Lin E, Kuo PH et al.

Oncotarget

Metabolic syndrome

2017-09-16

A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic pulmonary arterial hypertension in a Japanese population.

Kimura M, Tamura Y et al.

Oncotarget

Pulmonary arterial hypertension

2017-08-24

Genome-wide association study of high-altitude pulmonary edema in a Han Chinese population.

Li X, Jin T et al.

Oncotarget

High-altitude pulmonary edema

2017-03-18

TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer.

Fagerholm R, Khan S et al.

Oncotarget

Survival in breast cancer (TP53 expression interaction)

2017-03-14

Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.

Ransohoff KJ, Wu W et al.

Oncotarget

Melanoma

2017-02-09

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

Lv H, Zhang M et al.

Oncotarget

Core binding factor acute myeloid leukemia

2017-01-31

GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients.

Cox DG, Curtit E et al.

Oncotarget

Estrogen receptor status in HER2 positive breast cancer

2016-10-14

Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21.

Zhang M, Wang Z et al.

Oncotarget

Pancreatic cancer

2016-08-01