Active: Ankylosing spondylitis Clear all

GWAS 2025-04-22

The phenotypic and genetic association between endometriosis and immunological diseases.

Shigesi N, Harris HR et al.

Hum Reprod

Study question: Is there an increased risk of immunological diseases among endometriosis patients, a...

Ankylosing spondylitis

321025

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-27

Comprehensive association analyses of extraintestinal manifestations in inflammatory bowel disease.

Khrom M, Long M et al.

Gastroenterology

Background & aims: Patients with inflammatory bowel disease (IBD) frequently develop extraintest...

Extraintestinal manifestations in inflammatory bowel disease (ankylosing spondylitis and sacroiliitis)

12027

Participants

N/A

Studies

Details PubMed

GWAS 2023-08-24

Response to anti-IL17 therapy in inflammatory disease is not strongly impacted by genetic background.

Zhang C, Shestopaloff K et al.

Am J Hum Genet

Response to the anti-IL17 monoclonal antibody secukinumab is heterogeneous, and not all participants...

Erythrocyte sedimentation rate x secukinumab treatment interaction in ankylosing spondylitis

754

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-12

Genome-wide association study reveals ethnicity-specific SNPs associated with ankylosing spondylitis in the Taiwanese population.

Ko CL, Lin WZ et al.

J Transl Med

Ankylosing spondylitis (AS) is an autoimmune disease affecting mainly spine and sacroiliac joints an...

Ankylosing spondylitis

1442

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-10

CNest: A novel copy number association discovery method uncovers 862 new associations from 200,629 whole-exome sequence datasets in the UK Biobank.

Fitzgerald T, Birney E

Cell Genom

Copy number variation (CNV) is known to influence human traits, having a rich history of research in...

Source of report of M45 (ankylosing spondylitis) (UKB data field 131913)

170757

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-01

Genomewide Association Study of Acute Anterior Uveitis Identifies New Susceptibility Loci.

Huang XF, Li Z et al.

Invest Ophthalmol Vis Sci

Purpose: Acute anterior uveitis (AAU) is a common intraocular inflammatory disease. AAU occurs in 30...

Acute anterior uveitis in ankylosing spondylitis

6588

Participants

N/A

Studies

Details PubMed

GWAS 2019-04-04

Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis.

Li Z, Akar S et al.

PLoS Genet

Ankylosing spondylitis (AS) is a highly heritable immune-mediated arthritis common in Turkish and Ir...

Ankylosing spondylitis

3004

Participants

N/A

Studies

Details PubMed

GWAS 2016-03-14

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

Ellinghaus D, Jostins L et al.

Nat Genet

We simultaneously investigated the genetic landscape of ankylosing spondylitis, Crohn's disease, pso...

Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy)

86475

Participants

N/A

Studies

Details PubMed

GWAS 2014-09-08

Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis.

Robinson PC, Claushuis TA et al.

Arthritis Rheumatol

Objective: To use high-density genotyping to investigate the genetic associations of acute anterior ...

Acute anterior uveitis (with or without ankylosing spondylitis)

11001

Participants

N/A

Studies

Details PubMed

GWAS 2013-07-01

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.

Cortes A, Hadler J et al.

Nat Genet

Ankylosing spondylitis is a common, highly heritable inflammatory arthritis affecting primarily the ...

Ankylosing spondylitis

25764

Participants

N/A

Studies

Details PubMed

GWAS 2013-01-06

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.

Kirino Y, Bertsias G et al.

Nat Genet

Individuals with Behçet's disease suffer from episodic inflammation often affecting the orogenital m...

Behcet's disease

Replicated

5313

Participants

N/A

Studies

Details PubMed

GWAS 2012-11-01

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Jostins L, Ripke S et al.

Nature

Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease (IBD), af...

Crohn's disease

Replicated

77064

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

The phenotypic and genetic association between endometriosis and immunological diseases.

Shigesi N, Harris HR et al.

Hum Reprod

Ankylosing spondylitis

2025-04-22

Comprehensive association analyses of extraintestinal manifestations in inflammatory bowel disease.

Khrom M, Long M et al.

Gastroenterology

Extraintestinal manifestations in inflammatory bowel disease (ankylosing spondylitis and sacroiliitis)

2024-02-27

Response to anti-IL17 therapy in inflammatory disease is not strongly impacted by genetic background.

Zhang C, Shestopaloff K et al.

Am J Hum Genet

Erythrocyte sedimentation rate x secukinumab treatment interaction in ankylosing spondylitis

2023-08-24

Genome-wide association study reveals ethnicity-specific SNPs associated with ankylosing spondylitis in the Taiwanese population.

Ko CL, Lin WZ et al.

J Transl Med

Ankylosing spondylitis

2022-12-12

CNest: A novel copy number association discovery method uncovers 862 new associations from 200,629 whole-exome sequence datasets in the UK Biobank.

Fitzgerald T, Birney E

Cell Genom

Source of report of M45 (ankylosing spondylitis) (UKB data field 131913)

2022-08-10

Genomewide Association Study of Acute Anterior Uveitis Identifies New Susceptibility Loci.

Huang XF, Li Z et al.

Invest Ophthalmol Vis Sci

Acute anterior uveitis in ankylosing spondylitis

2020-06-01

Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis.

Li Z, Akar S et al.

PLoS Genet

Ankylosing spondylitis

2019-04-04

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

Ellinghaus D, Jostins L et al.

Nat Genet

Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy)

2016-03-14

Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis.

Robinson PC, Claushuis TA et al.

Arthritis Rheumatol

Acute anterior uveitis (with or without ankylosing spondylitis)

2014-09-08

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.

Cortes A, Hadler J et al.

Nat Genet

Ankylosing spondylitis

2013-07-01

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.

Kirino Y, Bertsias G et al.

Nat Genet

Behcet's disease

2013-01-06

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Jostins L, Ripke S et al.

Nature

Crohn's disease

2012-11-01