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GWAS Study

Genome-wide association study reveals ethnicity-specific SNPs associated with ankylosing spondylitis in the Taiwanese population.

Ko CL, Lin WZ, Lee MT et al.

36510243 PubMed ID
GWAS Study Type
1442 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KC
Ko CL
LW
Lin WZ
LM
Lee MT
CY
Chang YT
LH
Lin HC
WY
Wu YS
LJ
Lin JF
PK
Pan KT
CY
Chang YC
LK
Lee KH
LY
Lee YL
HT
Hsieh TT
HJ
Huang JH
WC
Wang CH
YS
Yang SS
CH
Chen HC
CC
Chu CM
Chapter II

Abstract

Summary of the research findings

Ankylosing spondylitis (AS) is an autoimmune disease affecting mainly spine and sacroiliac joints and adjacent soft tissues. Genome-wide association studies (GWASs) are used to evaluate genetic associations and to predict genetic risk factors that determine the biological basis of disease susceptibility. We aimed to explore the race-specific SNP susceptibility of AS in Taiwanese individuals and to investigate the association between HLA-B27 and AS susceptibility SNPs in Taiwan.

206 Taiwanese ancestry cases, 1,236 Taiwanese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1442
Total Participants
GWAS
Study Type
No
Replicated
East Asian
Ancestry
Taiwan
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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