Active: Coronary artery disease Clear all

GWAS 2025-09-29

Genetic analyses across cardiovascular traits: leveraging genetic correlations to empower locus discovery and prediction in common cardiovascular diseases.

Jordà P, Lai Y et al.

NPJ Genom Med

Common genetic variation detected by genome-wide association studies (GWAS) partially explains varia...

Atrial fibrillation (MTAG)

296021

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-13

Metabolome-wide association identifies ferredoxin-1 (FDX1) as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations.

Sadhu N, Dalan R et al.

Nat Cardiovasc Res

The burden of cardiovascular disease is rising in the Asia-Pacific region, in contrast to falling ca...

Tetradecadienoate (14:2) levels

1876

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-06

Unravelling genetic architecture of circulatory amino acid levels, and their effect on risk of complex disorders.

Abar L, Zuber V et al.

NAR Genom Bioinform

Variations in serum amino acid levels are linked to a multitude of complex disorders. We report the ...

Alanine levels

117944

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-13

Cardiovascular Significance and Genetics of Epicardial and Pericardial Adiposity.

Rämö JT, Kany S et al.

JAMA Cardiol

Importance: Epicardial and pericardial adipose tissue (EPAT) has been associated with cardiovascular...

Epicardial and pericardial adipose tissue

44356

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-19

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.

Suzuki K, Hatzikotoulas K et al.

Nature

Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological pr...

Type 2 diabetes

2535601

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-08

Bidirectional relationship between type 2 diabetes mellitus and coronary artery disease: Prospective cohort study and genetic analyses.

Zhang W, Zhang L et al.

Chin Med J (Engl)

While type 2 diabetes mellitus (T2DM) is considered a putative causal risk factor for coronary arter...

Type 2 diabetes mellitus or coronary artery disease (pleiotropy)

2063820

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-01

A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk.

Verdier H, Thomas P et al.

Blood

Genetic studies of platelet reactivity (PR) phenotypes may identify novel antiplatelet drug targets....

Predicted platelet reactivity

29806

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-31

Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.

Ottensmann L, Tabassum R et al.

Nat Commun

The human plasma lipidome captures risk for cardiometabolic diseases. To discover new lipid-associat...

Triacylglycerol (50:2) levels

7172

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-28

Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.

Kavousi M, Bos MM et al.

Nat Genet

Coronary artery calcification (CAC), a measure of subclinical atherosclerosis, predicts future sympt...

Coronary artery calcification

36720

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-13

Impact of gallstone disease on the risk of stroke and coronary artery disease: evidence from prospective observational studies and genetic analyses.

Zhang L, Zhang W et al.

BMC Med

Despite epidemiological evidence associating gallstone disease (GSD) with cardiovascular disease (CV...

Gall stone disease or stroke

1858897

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-30

A multivariate genome-wide association study of psycho-cardiometabolic multimorbidity.

Baltramonaityte V, Pingault JB et al.

PLoS Genet

Coronary artery disease (CAD), type 2 diabetes (T2D) and depression are among the leading causes of ...

Psycho-cardiometabolic multimorbidity (multivariate analysis)

562507

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-29

Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation.

Adlam D, Berrandou TE et al.

Nat Genet

Spontaneous coronary artery dissection (SCAD) is an understudied cause of myocardial infarction prim...

Spontaneous coronary artery dissection

11209

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic analyses across cardiovascular traits: leveraging genetic correlations to empower locus discovery and prediction in common cardiovascular diseases.

Jordà P, Lai Y et al.

NPJ Genom Med

Atrial fibrillation (MTAG)

2025-09-29

Metabolome-wide association identifies ferredoxin-1 (FDX1) as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations.

Sadhu N, Dalan R et al.

Nat Cardiovasc Res

Tetradecadienoate (14:2) levels

2025-05-13

Unravelling genetic architecture of circulatory amino acid levels, and their effect on risk of complex disorders.

Abar L, Zuber V et al.

NAR Genom Bioinform

Alanine levels

2024-05-06

Cardiovascular Significance and Genetics of Epicardial and Pericardial Adiposity.

Rämö JT, Kany S et al.

JAMA Cardiol

Epicardial and pericardial adipose tissue

2024-03-13

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.

Suzuki K, Hatzikotoulas K et al.

Nature

Type 2 diabetes

2024-02-19

Bidirectional relationship between type 2 diabetes mellitus and coronary artery disease: Prospective cohort study and genetic analyses.

Zhang W, Zhang L et al.

Chin Med J (Engl)

Type 2 diabetes mellitus or coronary artery disease (pleiotropy)

2023-12-08

A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk.

Verdier H, Thomas P et al.

Blood

Predicted platelet reactivity

2023-11-01

Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.

Ottensmann L, Tabassum R et al.

Nat Commun

Triacylglycerol (50:2) levels

2023-10-31

Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.

Kavousi M, Bos MM et al.

Nat Genet

Coronary artery calcification

2023-09-28

Impact of gallstone disease on the risk of stroke and coronary artery disease: evidence from prospective observational studies and genetic analyses.

Zhang L, Zhang W et al.

BMC Med

Gall stone disease or stroke

2023-09-13

A multivariate genome-wide association study of psycho-cardiometabolic multimorbidity.

Baltramonaityte V, Pingault JB et al.

PLoS Genet

Psycho-cardiometabolic multimorbidity (multivariate analysis)

2023-06-30

Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation.

Adlam D, Berrandou TE et al.

Nat Genet

Spontaneous coronary artery dissection

2023-05-29