Active: Depression Clear all

GWAS 2025-12-05

No causal links between estradiol and female's brain and mental health using Mendelian randomization.

Oppenheimer H, van der Meer D et al.

Nat Commun

The role of estradiol in depression and Alzheimer's disease - brain disorders that disproportionatel...

Brain age gap

13423

Participants

N/A

Studies

Details PubMed

GWAS 2025-07-28

Large-scale genome-wide analyses of stuttering.

Polikowsky HG, Scartozzi AC et al.

Nat Genet

Developmental stuttering is a highly heritable, common speech condition characterized by prolongatio...

Stuttering

13977

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-20

Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids.

Bentley AR, Brown MR et al.

Transl Psychiatry

Serum lipid levels, which are influenced by both genetic and environmental factors, are key determin...

HDL x anxiety interaction (1df test)

19133

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-10

Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes.

Assary E, Coleman JRI et al.

Nat Hum Behav

Individual sensitivity to environmental exposures may be genetically influenced. This genotype-by-en...

Monozygotic twin difference score for ADHD symptoms

6869

Participants

N/A

Studies

Details PubMed

GWAS 2025-01-28

Associations between common genetic variants and income provide insights about the socio-economic health gradient.

Kweon H, Burik CAP et al.

Nat Hum Behav

We conducted a genome-wide association study on income among individuals of European descent (N = 66...

Individual income

72601

Participants

N/A

Studies

Details PubMed

GWAS 2024-10-29

Whole exome sequencing identified six novel genes for depressive symptoms.

Li ZY, Fei CJ et al.

Mol Psychiatry

Previous genome-wide association studies of depression have primarily focused on common variants, li...

Depressive symptoms (sum-score)

296199

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-18

Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study.

Friligkou E, Løkhammer S et al.

Nat Genet

We leveraged information from more than 1.2 million participants, including 97,383 cases, to investi...

Anxiety disorder

1096458

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-18

Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression.

Zhukovsky P, Tio ES et al.

Nat Commun

Approximately 40% of dementia cases could be prevented or delayed by modifiable risk factors related...

Global cortical thickness (GlobalMeanMean)

34552

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-23

Genetic associations with psychosis and affective disturbance in Alzheimer's disease.

Antonsdottir IM, Creese B et al.

Alzheimers Dement (N Y)

Introduction: Individuals with Alzheimer's disease (AD) commonly experience neuropsychiatric symptom...

Psychosis in Alzheimer's disease

9988

Participants

N/A

Studies

Details PubMed

GWAS 2024-04-01

Genome-wide association study of early-onset and late-onset postpartum depression: the IGEDEPP prospective study.

Tebeka S, Gloaguen E et al.

Eur Psychiatry

Postpartum depression (PPD) appears at two peak periods: early-onset prior to 2 months after deliver...

Early-onset postpartum depression

1438

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-15

Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom Trajectory.

Ohseto H, Takahashi I et al.

Depress Anxiety

This study is aimed at revealing the risk factors, prognosis, influence on offspring, and genetic ar...

Perinatal depression

5098

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-28

Comprehensive Sex-Stratified Genetic Analysis of 28 Blood Biomarkers and Depression Reveals a Significant Association between Depression and Low Levels of Total Protein in Females.

Kiewa J, Meltzer-Brody S et al.

Complex Psychiatry

Introduction: Major depression (MD) is more common amongst women than men, and MD episodes have been...

Serum urate levels

236171

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

No causal links between estradiol and female's brain and mental health using Mendelian randomization.

Oppenheimer H, van der Meer D et al.

Nat Commun

Brain age gap

2025-12-05

Large-scale genome-wide analyses of stuttering.

Polikowsky HG, Scartozzi AC et al.

Nat Genet

Stuttering

2025-07-28

Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids.

Bentley AR, Brown MR et al.

Transl Psychiatry

HDL x anxiety interaction (1df test)

2025-06-20

Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes.

Assary E, Coleman JRI et al.

Nat Hum Behav

Monozygotic twin difference score for ADHD symptoms

2025-06-10

Associations between common genetic variants and income provide insights about the socio-economic health gradient.

Kweon H, Burik CAP et al.

Nat Hum Behav

Individual income

2025-01-28

Whole exome sequencing identified six novel genes for depressive symptoms.

Li ZY, Fei CJ et al.

Mol Psychiatry

Depressive symptoms (sum-score)

2024-10-29

Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study.

Friligkou E, Løkhammer S et al.

Nat Genet

Anxiety disorder

2024-09-18

Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression.

Zhukovsky P, Tio ES et al.

Nat Commun

Global cortical thickness (GlobalMeanMean)

2024-06-18

Genetic associations with psychosis and affective disturbance in Alzheimer's disease.

Antonsdottir IM, Creese B et al.

Alzheimers Dement (N Y)

Psychosis in Alzheimer's disease

2024-05-23

Genome-wide association study of early-onset and late-onset postpartum depression: the IGEDEPP prospective study.

Tebeka S, Gloaguen E et al.

Eur Psychiatry

Early-onset postpartum depression

2024-04-01

Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom Trajectory.

Ohseto H, Takahashi I et al.

Depress Anxiety

Perinatal depression

2024-03-15

Comprehensive Sex-Stratified Genetic Analysis of 28 Blood Biomarkers and Depression Reveals a Significant Association between Depression and Low Levels of Total Protein in Females.

Kiewa J, Meltzer-Brody S et al.

Complex Psychiatry

Serum urate levels

2024-02-28