Active: Diabetic retinopathy Clear all

GWAS 2025-02-04

Multi-omic spatial effects on high-resolution AI-derived retinal thickness.

Jackson VE, Wu Y et al.

Nat Commun

Retinal thickness is a marker of retinal health and more broadly, is seen as a promising biomarker f...

Retinal thickness (functional principal component 1)

Replicated

45488

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-23

Microvascular and macrovascular complications of type 2 diabetes mellitus: Exome wide association analyses.

Mansour A, Mousa M et al.

Front Endocrinol (Lausanne)

Type 2 diabetes mellitus (T2DM) is a chronic, metabolic disorder in which concomitant insulin resist...

Diabetic retinopathy in type 2 diabetes

310

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-13

Genome-wide association meta-analysis of 88,250 individuals highlights pleiotropic mechanisms of five ocular diseases in UK Biobank.

Xue Z, Yuan J et al.

EBioMedicine

Ocular diseases may exhibit common clinical symptoms and epidemiological comorbidity. However, the e...

Age-related macular degeneration

66387

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-06

Identifying Genetic Biomarkers Predicting Response to Anti-Vascular Endothelial Growth Factor Injections in Diabetic Macular Edema.

Gurung RL, FitzGerald LM et al.

Int J Mol Sci

Intraocular anti-vascular endothelial growth factor (VEGF) therapies are the front-line treatment fo...

Response to anti-vascular endothelial growth factor drug in diabetic macular edema (central macular thickness)

220

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-19

Genome-Wide Association Studies Identify Two Novel Loci Conferring Susceptibility to Diabetic Retinopathy in Japanese Patients with Type 2 Diabetes.

Imamura M, Takahashi A et al.

Hum Mol Genet

Several reports have suggested that genetic susceptibility contributes to the development and progre...

Diabetic retinopathy in type 2 diabetes

Replicated

15669

Participants

N/A

Studies

Details PubMed

GWAS 2020-01-01

Lack of association of genetic variants for diabetic retinopathy in Taiwanese patients with diabetic nephropathy.

Hsieh AR, Huang YC et al.

BMJ Open Diabetes Res Care

Objective: Diabetic nephropathy (DN) and diabetic retinopathy (DR) comprise major microvascular comp...

Diabetic retinopathy in type 2 diabetes

412

Participants

N/A

Studies

Details PubMed

GWAS 2019-08-29

Genome-wide association study for proliferative diabetic retinopathy in Africans.

Liu C, Chen G et al.

NPJ Genom Med

Proliferative diabetic retinopathy (PDR) is a sight-threatening complication of diabetes that is ass...

Proliferative diabetic retinopathy

Replicated

360

Participants

N/A

Studies

Details PubMed

GWAS 2019-07-02

A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.

Meng W, Chan BW et al.

Ophthalmic Genet

Diabetic maculopathy is a form of diabetic retinopathy. The visual acuity of one third of patients w...

Diabetic maculopathy with decreased visual acuity in type 2 diabetes

1843

Participants

N/A

Studies

Details PubMed

GWAS 2018-11-28

Multiethnic Genome-wide Association Study of Diabetic Retinopathy using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control.

Pollack S, Igo RP et al.

Diabetes

To identify genetic variants associated with diabetic retinopathy (DR), we performed a large multiet...

Diabetic retinopathy (all NPDR and PDR)

Replicated

39032

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-04

A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes.

Meng W, Shah KP et al.

Acta Ophthalmol

Purpose: Diabetic retinopathy is the most common eye complication in patients with diabetes. The pur...

Severe diabetic retinopathy in type 2 diabetes

4666

Participants

N/A

Studies

Details PubMed

GWAS 2018-05-08

Genome-wide association studies for diabetic macular edema and proliferative diabetic retinopathy.

Graham PS, Kaidonis G et al.

BMC Med Genet

Diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) are sight-threatening comp...

Diabetic macular edema in type 2 diabetes

705

Participants

N/A

Studies

Details PubMed

GWAS 2016-04-12

New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes Also Associated With Blood and Skin Glycated Proteins.

Roshandel D, Klein R et al.

Diabetes

Skin fluorescence (SF) noninvasively measures advanced glycation end products (AGEs) in the skin and...

Skin fluorescence in type 1 diabetes

1359

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Multi-omic spatial effects on high-resolution AI-derived retinal thickness.

Jackson VE, Wu Y et al.

Nat Commun

Retinal thickness (functional principal component 1)

2025-02-04

Microvascular and macrovascular complications of type 2 diabetes mellitus: Exome wide association analyses.

Mansour A, Mousa M et al.

Front Endocrinol (Lausanne)

Diabetic retinopathy in type 2 diabetes

2023-03-23

Genome-wide association meta-analysis of 88,250 individuals highlights pleiotropic mechanisms of five ocular diseases in UK Biobank.

Xue Z, Yuan J et al.

EBioMedicine

Age-related macular degeneration

2022-07-13

Identifying Genetic Biomarkers Predicting Response to Anti-Vascular Endothelial Growth Factor Injections in Diabetic Macular Edema.

Gurung RL, FitzGerald LM et al.

Int J Mol Sci

Response to anti-vascular endothelial growth factor drug in diabetic macular edema (central macular thickness)

2022-04-06

Genome-Wide Association Studies Identify Two Novel Loci Conferring Susceptibility to Diabetic Retinopathy in Japanese Patients with Type 2 Diabetes.

Imamura M, Takahashi A et al.

Hum Mol Genet

Diabetic retinopathy in type 2 diabetes

2021-02-19

Lack of association of genetic variants for diabetic retinopathy in Taiwanese patients with diabetic nephropathy.

Hsieh AR, Huang YC et al.

BMJ Open Diabetes Res Care

Diabetic retinopathy in type 2 diabetes

2020-01-01

Genome-wide association study for proliferative diabetic retinopathy in Africans.

Liu C, Chen G et al.

NPJ Genom Med

Proliferative diabetic retinopathy

2019-08-29

A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.

Meng W, Chan BW et al.

Ophthalmic Genet

Diabetic maculopathy with decreased visual acuity in type 2 diabetes

2019-07-02

Multiethnic Genome-wide Association Study of Diabetic Retinopathy using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control.

Pollack S, Igo RP et al.

Diabetes

Diabetic retinopathy (all NPDR and PDR)

2018-11-28

A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes.

Meng W, Shah KP et al.

Acta Ophthalmol

Severe diabetic retinopathy in type 2 diabetes

2018-09-04

Genome-wide association studies for diabetic macular edema and proliferative diabetic retinopathy.

Graham PS, Kaidonis G et al.

BMC Med Genet

Diabetic macular edema in type 2 diabetes

2018-05-08

New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes Also Associated With Blood and Skin Glycated Proteins.

Roshandel D, Klein R et al.

Diabetes

Skin fluorescence in type 1 diabetes

2016-04-12