A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes.
Meng W, Shah KP, Pollack S et al.
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Abstract
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Purpose: Diabetic retinopathy is the most common eye complication in patients with diabetes. The purpose of this study is to identify genetic factors contributing to severe diabetic retinopathy.
560 Scottish ancestry proliferative or severe background retinopathy cases, 4,106 Scottish ancestry mild or no retinopathy controls
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