Lack of association of genetic variants for diabetic retinopathy in Taiwanese patients with diabetic nephropathy.
Hsieh AR, Huang YC, Yang YF et al.
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Abstract
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Objective: Diabetic nephropathy (DN) and diabetic retinopathy (DR) comprise major microvascular complications of diabetes that occur with a high concordance rate in patients and are considered to potentially share pathogeneses. In this case-control study, we sought to investigate whether DR-related single nucleotide polymorphisms (SNPs) exert pleiotropic effects on renal function outcomes among patients with diabetes.
206 East Asian ancestry cases, 206 East Asian ancestry controls
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