Active: Esophageal adenocarcinoma Clear all

GWAS 2025-07-01

Investigating the shared genetic architecture between adiposity measures and obesity-related cancers.

Wang S, Liu H et al.

Brief Bioinform

Fat distribution patterns are increasingly linked to obesity-related cancers; however, their shared ...

Leg fat ratio or ovarian cancer (pleiotropy)

127582

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-18

Dissecting the genetic heterogeneity of gastric cancer.

Hess T, Maj C et al.

EBioMedicine

Gastric cancer (GC) is clinically heterogenous according to location (cardia/non-cardia) and histopa...

Gastric cancer

16814

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-26

GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.

Schröder J, Chegwidden L et al.

Gut

Objective: Oesophageal cancer (EC) is the sixth leading cause of cancer-related deaths. Oesophageal ...

Barrett's esophagus or Esophageal adenocarcinoma

49266

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-09

Sex-Specific Genetic Associations for Barrett's Esophagus and Esophageal Adenocarcinoma.

Dong J, Maj C et al.

Gastroenterology

Background & aims: Esophageal adenocarcinoma (EA) and its premalignant lesion, Barrett's esophag...

Barrett's esophagus or esophageal adenocarcinoma x sex interaction (1df test)

22091

Participants

N/A

Studies

Details PubMed

GWAS 2019-09-16

Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases.

An J, Gharahkhani P et al.

Nat Commun

Gastroesophageal reflux disease (GERD) is caused by gastric acid entering the esophagus. GERD has hi...

Barrett's esophagus or Esophageal adenocarcinoma

32925

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-15

Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus.

Dong J, Levine DM et al.

Clin Gastroenterol Hepatol

Background & aims: Genome-wide association studies (GWAS) have identified more than 20 susceptib...

Esophageal adenocarcinoma x BMI interaction

4466

Participants

N/A

Studies

Details PubMed

GWAS 2016-08-12

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.

Gharahkhani P, Fitzgerald RC et al.

Lancet Oncol

Oesophageal adenocarcinoma represents one of the fastest rising cancers in high-income countries. Ba...

Barrett's esophagus

23326

Participants

N/A

Studies

Details PubMed

GWAS 2013-10-13

A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.

Levine DM, Ek WE et al.

Nat Genet

Esophageal adenocarcinoma is a cancer with rising incidence and poor survival. Most such cancers ari...

Esophageal adenocarcinoma

Replicated

13227

Participants

N/A

Studies

Details PubMed

GWAS 2012-09-09

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.

Su Z, Gay LJ et al.

Nat Genet

Barrett's esophagus is an increasingly common disease that is strongly associated with reflux of sto...

Barrett's esophagus

Replicated

25835

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Investigating the shared genetic architecture between adiposity measures and obesity-related cancers.

Wang S, Liu H et al.

Brief Bioinform

Leg fat ratio or ovarian cancer (pleiotropy)

2025-07-01

Dissecting the genetic heterogeneity of gastric cancer.

Hess T, Maj C et al.

EBioMedicine

Gastric cancer

2023-05-18

GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.

Schröder J, Chegwidden L et al.

Gut

Barrett's esophagus or Esophageal adenocarcinoma

2022-07-26

Sex-Specific Genetic Associations for Barrett's Esophagus and Esophageal Adenocarcinoma.

Dong J, Maj C et al.

Gastroenterology

Barrett's esophagus or esophageal adenocarcinoma x sex interaction (1df test)

2020-09-09

Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases.

An J, Gharahkhani P et al.

Nat Commun

Barrett's esophagus or Esophageal adenocarcinoma

2019-09-16

Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus.

Dong J, Levine DM et al.

Clin Gastroenterol Hepatol

Esophageal adenocarcinoma x BMI interaction

2018-03-15

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.

Gharahkhani P, Fitzgerald RC et al.

Lancet Oncol

Barrett's esophagus

2016-08-12

A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.

Levine DM, Ek WE et al.

Nat Genet

Esophageal adenocarcinoma

2013-10-13

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.

Su Z, Gay LJ et al.

Nat Genet

Barrett's esophagus

2012-09-09