Active: Inflammatory biomarkers Clear all

GWAS 2024-05-15

Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium.

Jiang MZ, Gaynor SM et al.

Hum Mol Genet

Inflammation biomarkers can provide valuable insight into the role of inflammatory processes in many...

CD40 levels

2381

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-08

Sex-biased genetic regulation of inflammatory proteins in the Dutch population.

Boahen CK, Abee H et al.

BMC Genomics

Significant differences in immune responses, prevalence or susceptibility of diseases and treatment ...

CXCL9 levels

318

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-28

Genome-wide analysis of oxylipins and oxylipin profiles in a pediatric population.

Buckner T, Johnson RK et al.

Front Nutr

Oxylipins are inflammatory biomarkers derived from omega-3 and-6 fatty acids implicated in inflammat...

Plasma oxylipin 12,13-dihydroxyoctadec-9-enoic acid levels

316

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-27

An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease.

Ruotsalainen SE, Partanen JJ et al.

Eur J Hum Genet

Multivariate methods are known to increase the statistical power to detect associations in the case ...

Inflammatory biomarkers (multivariate analysis)

6890

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-14

Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study.

Jung SY, Scott PA et al.

Cancer Prev Res (Phila)

Immune-related etiologic pathways to influence invasive breast cancer risk may interact with lifesty...

Serum C-reactive protein concentration

10798

Participants

N/A

Studies

Details PubMed

GWAS 2019-11-14

Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers.

Höglund J, Rafati N et al.

Sci Rep

Genome-wide association studies (GWAS) have identified associations between thousands of common gene...

Inflammatory biomarkers

957

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-17

Family-based genome-wide association of inflammation biomarkers and fenofibrate treatment response in the GOLDN study.

Das S, Mondal PK et al.

BMC Proc

In this paper we analyzed whole-genome genetic information provided by GAW20 from the Genetics of Li...

Response to fenofibrate

778

Participants

N/A

Studies

Details PubMed

GWAS 2017-08-19

Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study.

Veenstra J, Kalsbeek A et al.

Nutrients

Numerous genetic loci have been identified as being associated with circulating fatty acid (FA) leve...

Interleukin-6 (red blood cell fatty acid level interaction)

2703

Participants

N/A

Studies

Details PubMed

GWAS 2014-09-30

Common variants in the CRP promoter are associated with a high C-reactive protein level in Kawasaki disease.

Kim JJ, Yun SW et al.

Pediatr Cardiol

Kawasaki disease (KD) is an acute self-limiting form of vasculitis that afflicts infants and childre...

Inflammatory biomarkers in Kawasaki disease

Replicated

651

Participants

N/A

Studies

Details PubMed

GWAS 2013-10-29

Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults.

Matteini AM, Li J et al.

Cytokine

Activation of inflammatory pathways measured by serum inflammatory markers such as interleukin-18 (I...

Inflammatory biomarkers

4443

Participants

N/A

Studies

Details PubMed

GWAS 2012-01-26

A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation.

Naitza S, Porcu E et al.

PLoS Genet

Identifying the genes that influence levels of pro-inflammatory molecules can help to elucidate the ...

Inflammatory biomarkers

Replicated

6086

Participants

N/A

Studies

Details PubMed

GWAS 2012-01-05

A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.

Aslibekyan S, Kabagambe EK et al.

Pharmacogenet Genomics

Objective: Despite the evidence in support of the anti-inflammatory and triglyceride-lowering effect...

Inflammatory biomarkers

1092

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium.

Jiang MZ, Gaynor SM et al.

Hum Mol Genet

CD40 levels

2024-05-15

Sex-biased genetic regulation of inflammatory proteins in the Dutch population.

Boahen CK, Abee H et al.

BMC Genomics

CXCL9 levels

2024-02-08

Genome-wide analysis of oxylipins and oxylipin profiles in a pediatric population.

Buckner T, Johnson RK et al.

Front Nutr

Plasma oxylipin 12,13-dihydroxyoctadec-9-enoic acid levels

2023-03-28

An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease.

Ruotsalainen SE, Partanen JJ et al.

Eur J Hum Genet

Inflammatory biomarkers (multivariate analysis)

2020-10-27

Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study.

Jung SY, Scott PA et al.

Cancer Prev Res (Phila)

Serum C-reactive protein concentration

2020-09-14

Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers.

Höglund J, Rafati N et al.

Sci Rep

Inflammatory biomarkers

2019-11-14

Family-based genome-wide association of inflammation biomarkers and fenofibrate treatment response in the GOLDN study.

Das S, Mondal PK et al.

BMC Proc

Response to fenofibrate

2018-09-17

Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study.

Veenstra J, Kalsbeek A et al.

Nutrients

Interleukin-6 (red blood cell fatty acid level interaction)

2017-08-19

Common variants in the CRP promoter are associated with a high C-reactive protein level in Kawasaki disease.

Kim JJ, Yun SW et al.

Pediatr Cardiol

Inflammatory biomarkers in Kawasaki disease

2014-09-30

Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults.

Matteini AM, Li J et al.

Cytokine

Inflammatory biomarkers

2013-10-29

A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation.

Naitza S, Porcu E et al.

PLoS Genet

Inflammatory biomarkers

2012-01-26

A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.

Aslibekyan S, Kabagambe EK et al.

Pharmacogenet Genomics

Inflammatory biomarkers

2012-01-05