Active: Juvenile idiopathic arthritis Clear all

GWAS 2024-02-05

Revealing Novel Genomic Insights and Therapeutic Targets for Juvenile Idiopathic Arthritis through Omics.

Fan J, Li X et al.

Rheumatology (Oxford)

The genetic architecture of JIA remains only partially comprehended. There is a clear imperative for...

Juvenile idiopathic arthritis

22996

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-29

Identification of Novel Loci Shared by Juvenile Idiopathic Arthritis Subtypes through Integrative Genetic Analysis.

Li J, Li YR et al.

Arthritis Rheumatol

Objective: Juvenile idiopathic arthritis (JIA) is the most common chronic immune-mediated joint dise...

Arthritis (juvenile idiopathic)

10495

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-08

Association analysis of juvenile idiopathic arthritis genetic susceptibility factors in Estonian patients.

Nikopensius T, Niibo P et al.

Clin Rheumatol

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic condition of childhood. Gen...

Arthritis (juvenile idiopathic)

7219

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-26

Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms.

López-Isac E, Smith SL et al.

Ann Rheum Dis

Objectives: Juvenile idiopathic arthritis (JIA) is the most prevalent form of juvenile rheumatic dis...

Arthritis (juvenile idiopathic)

Replicated

31138

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-07

An amino acid motif in HLA-DRβ1 distinguishes patients with uveitis in juvenile idiopathic arthritis.

Haasnoot AJW, Schilham MW et al.

Arthritis Rheumatol

Objective: Uveitis is a visually debilitating disorder that affects up to 30% of children with the m...

Arthritis (juvenile idiopathic)

920

Participants

N/A

Studies

Details PubMed

GWAS 2016-12-07

Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.

Ombrello MJ, Arthur VL et al.

Ann Rheum Dis

Objectives: Juvenile idiopathic arthritis (JIA) is a heterogeneous group of conditions unified by th...

Systemic juvenile idiopathic arthritis

7717

Participants

N/A

Studies

Details PubMed

GWAS 2016-03-22

Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility.

Finkel TH, Li J et al.

BMC Med Genet

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease among children, the...

Arthritis (juvenile idiopathic)

Replicated

10666

Participants

N/A

Studies

Details PubMed

GWAS 2015-04-01

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

Onengut-Gumuscu S, Chen WM et al.

Nat Genet

Genetic studies of type 1 diabetes (T1D) have identified 50 susceptibility regions, finding major pa...

Type 1 diabetes

29652

Participants

N/A

Studies

Details PubMed

GWAS 2014-04-08

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.

Cobb J, Cule E et al.

Pharmacogenomics J

Clinical response to methotrexate (MTX) treatment for children with juvenile idiopathic arthritis (J...

Response to methotrexate in juvenile idiopathic arthritis

694

Participants

N/A

Studies

Details PubMed

GWAS 2013-04-21

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.

Hinks A, Cobb J et al.

Nat Genet

We used the Immunochip array to analyze 2,816 individuals with juvenile idiopathic arthritis (JIA), ...

Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)

15872

Participants

N/A

Studies

Details PubMed

GWAS 2012-02-21

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

Thompson SD, Marion MC et al.

Arthritis Rheum

Objective: In a genome-wide association study of Caucasian patients with juvenile idiopathic arthrit...

Arthritis (juvenile idiopathic)

Replicated

12626

Participants

N/A

Studies

Details PubMed

GWAS 2009-01-01

Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis.

Hinks A, Barton A et al.

Arthritis Rheum

Objective: Juvenile idiopathic arthritis (JIA) is a chronic rheumatic disease of childhood. Two well...

Arthritis (juvenile idiopathic)

Replicated

3141

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Revealing Novel Genomic Insights and Therapeutic Targets for Juvenile Idiopathic Arthritis through Omics.

Fan J, Li X et al.

Rheumatology (Oxford)

Juvenile idiopathic arthritis

2024-02-05

Identification of Novel Loci Shared by Juvenile Idiopathic Arthritis Subtypes through Integrative Genetic Analysis.

Li J, Li YR et al.

Arthritis Rheumatol

Arthritis (juvenile idiopathic)

2022-03-29

Association analysis of juvenile idiopathic arthritis genetic susceptibility factors in Estonian patients.

Nikopensius T, Niibo P et al.

Clin Rheumatol

Arthritis (juvenile idiopathic)

2021-06-08

Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms.

López-Isac E, Smith SL et al.

Ann Rheum Dis

Arthritis (juvenile idiopathic)

2020-10-26

An amino acid motif in HLA-DRβ1 distinguishes patients with uveitis in juvenile idiopathic arthritis.

Haasnoot AJW, Schilham MW et al.

Arthritis Rheumatol

Arthritis (juvenile idiopathic)

2018-03-07

Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.

Ombrello MJ, Arthur VL et al.

Ann Rheum Dis

Systemic juvenile idiopathic arthritis

2016-12-07

Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility.

Finkel TH, Li J et al.

BMC Med Genet

Arthritis (juvenile idiopathic)

2016-03-22

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

Onengut-Gumuscu S, Chen WM et al.

Nat Genet

Type 1 diabetes

2015-04-01

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.

Cobb J, Cule E et al.

Pharmacogenomics J

Response to methotrexate in juvenile idiopathic arthritis

2014-04-08

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.

Hinks A, Cobb J et al.

Nat Genet

Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)

2013-04-21

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

Thompson SD, Marion MC et al.

Arthritis Rheum

Arthritis (juvenile idiopathic)

2012-02-21

Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis.

Hinks A, Barton A et al.

Arthritis Rheum

Arthritis (juvenile idiopathic)

2009-01-01