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GWAS Study

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

Thompson SD, Marion MC, Sudman M et al.

22354554 PubMed ID
GWAS Study Type
12626 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TS
Thompson SD
MM
Marion MC
SM
Sudman M
RM
Ryan M
TM
Tsoras M
HT
Howard TD
BM
Barnes MG
RP
Ramos PS
TW
Thomson W
HA
Hinks A
HJ
Haas JP
PS
Prahalad S
BJ
Bohnsack JF
WC
Wise CA
PM
Punaro M
RC
Rosé CD
PN
Pajewski NM
SM
Spigarelli M
KM
Keddache M
WM
Wagner M
LC
Langefeld CD
GD
Glass DN
Chapter II

Abstract

Summary of the research findings

Objective: In a genome-wide association study of Caucasian patients with juvenile idiopathic arthritis (JIA), we have previously described findings limited to autoimmunity loci shared by JIA and other diseases. The present study was undertaken to identify novel JIA-predisposing loci using genome-wide approaches.

814 European ancestry cases, 658 European ancestry controls, 2,400 controls

Chapter III

Study Statistics

Key metrics and study information

12626
Total Participants
GWAS
Study Type
Yes
Replicated
1,744 European ancestry cases, 7,010 European ancestry controls
Replication Participants
European
Ancestry
U.S., Germany, U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

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