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GWAS Study

Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility.

Finkel TH, Li J, Wei Z et al.

27005825 PubMed ID
GWAS Study Type
10666 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

FT
Finkel TH
LJ
Li J
WZ
Wei Z
WW
Wang W
ZH
Zhang H
BE
Behrens EM
RE
Reuschel EL
LS
Limou S
WC
Wise C
PM
Punaro M
BM
Becker ML
MJ
Munro JE
FB
Flatø B
Førre Ø
TS
Thompson SD
LC
Langefeld CD
GD
Glass DN
GJ
Glessner JT
KC
Kim CE
FE
Frackelton E
SD
Shivers DK
TK
Thomas KA
CR
Chiavacci RM
HC
Hou C
XK
Xu K
SJ
Snyder J
QH
Qiu H
MF
Mentch F
WK
Wang K
WC
Winkler CA
LB
Lie BA
EJ
Ellis JA
HH
Hakonarson H
Chapter II

Abstract

Summary of the research findings

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease among children, the etiology of which involves a strong genetic component, but much of the underlying genetic determinants still remain unknown. Our aim was to identify novel genetic variants that predispose to JIA.

388 European ancestry cases, 2,500 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

10666
Total Participants
GWAS
Study Type
Yes
Replicated
778 European ancestry cases, 7,000 European ancestry controls
Replication Participants
European
Ancestry
U.S., Australia, Norway
Recruitment Country
Chapter IV

AI-Generated Summary

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