Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility.
Finkel TH, Li J, Wei Z et al.
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Abstract
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Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease among children, the etiology of which involves a strong genetic component, but much of the underlying genetic determinants still remain unknown. Our aim was to identify novel genetic variants that predispose to JIA.
388 European ancestry cases, 2,500 European ancestry controls
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