Active: Mean corpuscular hemoglobin Clear all

GWAS 2021-04-21

Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program.

Hu Y, Stilp AM et al.

Am J Hum Genet

Whole-genome sequencing (WGS), a powerful tool for detecting novel coding and non-coding disease-cau...

Hematocrit

62487

Participants

N/A

Studies

Details PubMed

GWAS 2017-05-13

Genome-wide association study of erythrocyte density in sickle cell disease patients.

Ilboudo Y, Bartolucci P et al.

Blood Cells Mol Dis

Deoxy-hemoglobin S polymerization into rigid fibers is the direct cause of the clinical sequelae obs...

Mean corpuscular hemoglobin concentration in sickle cell disease

317

Participants

N/A

Studies

Details PubMed

GWAS 2017-04-28

Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.

Hodonsky CJ, Jain D et al.

PLoS Genet

Prior GWAS have identified loci associated with red blood cell (RBC) traits in populations of Europe...

Hematocrit

Replicated

19608

Participants

N/A

Studies

Details PubMed

GWAS 2016-12-22

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.

van Rooij FJA, Qayyum R et al.

Am J Hum Genet

Genome-wide association studies (GWASs) have identified loci for erythrocyte traits in primarily Eur...

Mean corpuscular volume

Replicated

67259

Participants

N/A

Studies

Details PubMed

GWAS 2013-07-31

Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans.

Pistis G, Okonkwo SU et al.

PLoS One

The red blood cell related traits are highly heritable but their genetics are poorly defined. Only 5...

Red blood cell traits

Replicated

18428

Participants

N/A

Studies

Details PubMed

GWAS 2013-05-20

Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.

Ding K, de Andrade M et al.

G3 (Bethesda)

To identify novel genetic loci influencing interindividual variation in red blood cell (RBC) traits ...

Red blood cell traits

Replicated

2315

Participants

N/A

Studies

Details PubMed

GWAS 2012-12-20

GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.

Li J, Glessner JT et al.

Hum Mol Genet

Hematological traits are important clinical indicators, the genetic determinants of which have not b...

Mean corpuscular hemoglobin

14177

Participants

N/A

Studies

Details PubMed

GWAS 2010-12-31

Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.

Okada Y, Takahashi A et al.

Hum Mol Genet

C-reactive protein (CRP) is a hallmark acute-phase reactant and is widely used as a blood marker for...

C-reactive protein

Replicated

12854

Participants

N/A

Studies

Details PubMed

GWAS 2009-10-11

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.

Ganesh SK, Zakai NA et al.

Nat Genet

Measurements of erythrocytes within the blood are important clinical traits and can indicate various...

Mean corpuscular hemoglobin

Replicated

33623

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program.

Hu Y, Stilp AM et al.

Am J Hum Genet

Hematocrit

2021-04-21

Genome-wide association study of erythrocyte density in sickle cell disease patients.

Ilboudo Y, Bartolucci P et al.

Blood Cells Mol Dis

Mean corpuscular hemoglobin concentration in sickle cell disease

2017-05-13

Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.

Hodonsky CJ, Jain D et al.

PLoS Genet

Hematocrit

2017-04-28

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.

van Rooij FJA, Qayyum R et al.

Am J Hum Genet

Mean corpuscular volume

2016-12-22

Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans.

Pistis G, Okonkwo SU et al.

PLoS One

Red blood cell traits

2013-07-31

Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.

Ding K, de Andrade M et al.

G3 (Bethesda)

Red blood cell traits

2013-05-20

GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.

Li J, Glessner JT et al.

Hum Mol Genet

Mean corpuscular hemoglobin

2012-12-20

Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.

Okada Y, Takahashi A et al.

Hum Mol Genet

C-reactive protein

2010-12-31

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.

Ganesh SK, Zakai NA et al.

Nat Genet

Mean corpuscular hemoglobin

2009-10-11