Active: Warfarin maintenance dose Clear all

GWAS 2017-07-07

Influence of common and rare genetic variation on warfarin dose among African-Americans and European-Americans using the exome array.

Liu N, Irvin MR et al.

Pharmacogenomics

Aim: We conducted a genome-wide association study using the Illumina Exome Array to identify coding ...

Warfarin maintenance dose (adjusted for clinical factors)

Replicated

1707

Participants

N/A

Studies

Details PubMed

GWAS 2015-08-12

Genome-wide association study of warfarin maintenance dose in a Brazilian sample.

Parra EJ, Botton MR et al.

Pharmacogenomics

Aim: Extreme discordant phenotype and genome-wide association (GWA) approaches were combined to expl...

Warfarin maintenance dose

Replicated

2967

Participants

N/A

Studies

Details PubMed

GWAS 2013-06-05

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.

Perera MA, Cavallari LH et al.

Lancet

VKORC1 and CYP2C9 are important contributors to warfarin dose variability, but explain less variabil...

Warfarin maintenance dose

Replicated

965

Participants

N/A

Studies

Details PubMed

GWAS 2010-09-10

Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.

Cha PC, Mushiroda T et al.

Hum Mol Genet

Warfarin is a commonly used anticoagulant, whose dose needs to be determined for each individual pat...

Warfarin maintenance dose

Replicated

1952

Participants

N/A

Studies

Details PubMed

GWAS 2009-03-20

A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.

Takeuchi F, McGinnis R et al.

PLoS Genet

We report the first genome-wide association study (GWAS) whose sample size (1,053 Swedish subjects) ...

Warfarin maintenance dose

Replicated

1641

Participants

N/A

Studies

Details PubMed

GWAS 2008-06-05

A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.

Cooper GM, Johnson JA et al.

Blood

Warfarin dosing is correlated with polymorphisms in vitamin K epoxide reductase complex 1 (VKORC1) a...

Warfarin maintenance dose

Replicated

555

Participants

N/A

Studies

Details PubMed

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Disease/Trait

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Influence of common and rare genetic variation on warfarin dose among African-Americans and European-Americans using the exome array.

Liu N, Irvin MR et al.

Pharmacogenomics

Warfarin maintenance dose (adjusted for clinical factors)

2017-07-07

Genome-wide association study of warfarin maintenance dose in a Brazilian sample.

Parra EJ, Botton MR et al.

Pharmacogenomics

Warfarin maintenance dose

2015-08-12

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.

Perera MA, Cavallari LH et al.

Lancet

Warfarin maintenance dose

2013-06-05

Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.

Cha PC, Mushiroda T et al.

Hum Mol Genet

Warfarin maintenance dose

2010-09-10

A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.

Takeuchi F, McGinnis R et al.

PLoS Genet

Warfarin maintenance dose

2009-03-20

A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.

Cooper GM, Johnson JA et al.

Blood

Warfarin maintenance dose

2008-06-05