Active: White blood cell count Clear all

GWAS 2025-05-28

Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.

Jee YH, Wang Y et al.

Nat Commun

Genome-wide association studies (GWAS) have predominantly focused on European ancestry populations, ...

White blood cell count

928679

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-06

Genomic analysis of venous thrombosis in children with acute lymphoblastic leukemia from diverse ancestries.

Zheng Y, Yang W et al.

Haematologica

Venous thrombosis is a common adverse effect of modern therapy for acute lymphoblastic leukemia (ALL...

983

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-04

Height-Related Polygenic Variants Are Associated with Metabolic Syndrome Risk and Interact with Energy Intake and a Rice-Main Diet to Influence Height in KoGES.

Park S

Nutrients

Adult height is inversely related to metabolic syndrome (MetS) risk, but its genetic impacts have no...

Height

Replicated

72484

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-17

Interplay Between Hereditary and Acquired Factors Determine Neutrophil Counts in Aging Individuals.

Gagnon MF, Provost S et al.

Blood Adv

Blood cell production is a complex process, partly genetically determined and influenced by acquired...

White blood cell count

2465

Participants

N/A

Studies

Details PubMed

GWAS 2022-05-02

Genome-wide association and Mendelian randomization study of blood copper levels and 213 deep phenotypes in humans.

Yang W, Li L et al.

Commun Biol

Metal elements are present in the human body, and their levels in the blood have important impacts o...

Plasma cadmium levels

656

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-22

Characteristics of white blood cell count in acute lymphoblastic leukemia: A COST LEGEND phenotype-genotype study.

Helenius M, Vaitkeviciene G et al.

Pediatr Blood Cancer

White blood cell count (WBC) as a measure of extramedullary leukemic cell survival is a well-known p...

Log white blood cell count in acute lymphoblastic leukemia

1698

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-27

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Mikhaylova AV, McHugh CP et al.

Am J Hum Genet

Many common and rare variants associated with hematologic traits have been discovered through imputa...

White blood cell count

Replicated

260928

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-19

Association between Polygenetic Risk Scores of Low Immunity and Interactions between These Scores and Moderate Fat Intake in a Large Cohort.

Park S, Kang S

Nutrients

White blood cell (WBC) counts represent overall immunity. However, a few studies have been conducted...

Low white blood cell count

Replicated

46220

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-09

Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study.

Hu Y, Bien SA et al.

BMC Genomics

Circulating white blood cell and platelet traits are clinically linked to various disease outcomes a...

White blood cell count (basophil)

Replicated

27236

Participants

N/A

Studies

Details PubMed

GWAS 2020-12-31

Deciphering the genetic and epidemiological landscape of mitochondrial DNA abundance.

Hägg S, Jylhävä J et al.

Hum Genet

Mitochondrial (MT) dysfunction is a hallmark of aging and has been associated with most aging-relate...

Mitochondrial DNA levels

295150

Participants

N/A

Studies

Details PubMed

GWAS 2019-12-23

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.

Kowalski MH, Qian H et al.

PLoS Genet

Most genome-wide association and fine-mapping studies to date have been conducted in individuals of ...

Hematocrit

Replicated

50231

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-29

Analyses of genome wide association data, cytokines, and gene expression in African-Americans with benign ethnic neutropenia.

Charles BA, Hsieh MM et al.

PLoS One

Benign ethnic neutropenia (BEN) is a hematologic condition associated with people of African ancestr...

Low white blood cell count

1997

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.

Jee YH, Wang Y et al.

Nat Commun

White blood cell count

2025-05-28

Genomic analysis of venous thrombosis in children with acute lymphoblastic leukemia from diverse ancestries.

Zheng Y, Yang W et al.

Haematologica

—

2023-07-06

Park S

Nutrients

Height

2023-04-04

Interplay Between Hereditary and Acquired Factors Determine Neutrophil Counts in Aging Individuals.

Gagnon MF, Provost S et al.

Blood Adv

White blood cell count

2023-03-17

Genome-wide association and Mendelian randomization study of blood copper levels and 213 deep phenotypes in humans.

Yang W, Li L et al.

Commun Biol

Plasma cadmium levels

2022-05-02

Characteristics of white blood cell count in acute lymphoblastic leukemia: A COST LEGEND phenotype-genotype study.

Helenius M, Vaitkeviciene G et al.

Pediatr Blood Cancer

Log white blood cell count in acute lymphoblastic leukemia

2022-03-22

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Mikhaylova AV, McHugh CP et al.

Am J Hum Genet

White blood cell count

2021-09-27

Association between Polygenetic Risk Scores of Low Immunity and Interactions between These Scores and Moderate Fat Intake in a Large Cohort.

Park S, Kang S

Nutrients

Low white blood cell count

2021-08-19

Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study.

Hu Y, Bien SA et al.

BMC Genomics

White blood cell count (basophil)

2021-06-09

Deciphering the genetic and epidemiological landscape of mitochondrial DNA abundance.

Hägg S, Jylhävä J et al.

Hum Genet

Mitochondrial DNA levels

2020-12-31

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.

Kowalski MH, Qian H et al.

PLoS Genet

Hematocrit

2019-12-23

Analyses of genome wide association data, cytokines, and gene expression in African-Americans with benign ethnic neutropenia.

Charles BA, Hsieh MM et al.

PLoS One

Low white blood cell count

2018-03-29