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GWAS Study

Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study.

Hu Y, Bien SA, Nishimura KK et al.

34107879 PubMed ID
GWAS Study Type
27236 Participants
163 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HY
Hu Y
BS
Bien SA
NK
Nishimura KK
HJ
Haessler J
HC
Hodonsky CJ
BA
Baldassari AR
HH
Highland HM
WZ
Wang Z
PM
Preuss M
SC
Sitlani CM
WG
Wojcik GL
TR
Tao R
GM
Graff M
HL
Huckins LM
SQ
Sun Q
CM
Chen MH
MA
Mousas A
AP
Auer PL
LG
Lettre G
TW
Tang W
QL
Qi L
TB
Thyagarajan B
BS
Buyske S
FM
Fornage M
HL
Hindorff LA
LY
Li Y
LD
Lin D
RA
Reiner AP
NK
North KE
LR
Loos RJF
RL
Raffield LM
PU
Peters U
AC
Avery CL
KC
Kooperberg C
Chapter II

Abstract

Summary of the research findings

Circulating white blood cell and platelet traits are clinically linked to various disease outcomes and differ across individuals and ancestry groups. Genetic factors play an important role in determining these traits and many loci have been identified. However, most of these findings were identified in populations of European ancestry (EA), with African Americans (AA), Hispanics/Latinos (HL), and other races/ethnicities being severely underrepresented.

27,236 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

27236
Total Participants
GWAS
Study Type
Yes
Replicated
728,194 European ancestry, East Asian ancestry, African American or Afro-Caribbean, Hispanic or Latin American, South Asian ancestry individuals
Replication Participants
European, African American or Afro-Caribbean, Hispanic or Latin American, East Asian, African American or Afro-Caribbean, Hispanic or Latin American, South Asian
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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