Active: Alcohol Clin Exp Res Clear all

GWAS 2019-04-22

Multivariate analyses reveal biological components related to neuronal signaling and immunity mediating EEG abnormalities in alcohol-dependent individuals from the COGA cohort.

Meda SA, Narayanan B et al.

Alcohol Clin Exp Res

The underlying molecular mechanisms associated with alcohol use disorder (AUD) risk have only been p...

Alcohol use disorder

799

Participants

N/A

Studies

Details PubMed

GWAS 2018-12-27

Biomarker and genomic risk factors for liver function test abnormality in hazardous drinkers.

Whitfield JB, Zhu G et al.

Alcohol Clin Exp Res

Alcohol dependence and long-term excessive alcohol use may cause liver damage, but only some patient...

Gamma glutamyl transferase levels in excessive alcohol consumption

951

Participants

N/A

Studies

Details PubMed

GWAS 2018-10-01

Meta-Analysis of Genetic Influences on Initial Alcohol Sensitivity.

Edwards AC, Deak JD et al.

Alcohol Clin Exp Res

Previous studies indicate that low initial sensitivity to alcohol may be a risk factor for later alc...

Initial alcohol sensitivity

7339

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-25

Risk locus identification ties alcohol withdrawal symptoms to SORCS2.

Smith AH, Ovesen PL et al.

Alcohol Clin Exp Res

Efforts to promote the cessation of harmful alcohol use are hindered by the affective and physiologi...

Alcohol withdrawal symptoms

Replicated

1231

Participants

N/A

Studies

Details PubMed

GWAS 2018-02-20

Genomewide association study of alcohol dependence and related traits in a Thai population.

Gelernter J, Zhou H et al.

Alcohol Clin Exp Res

Alcohol use (both quantity and dependence) is moderately heritable, and genomewide association studi...

Alcohol dependence symptom count

1045

Participants

N/A

Studies

Details PubMed

GWAS 2015-07-04

Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use.

Clark SL, Aberg KA et al.

Alcohol Clin Exp Res

Methylome-wide association (MWAS) studies present a new way to advance the search for biological cor...

Alcohol consumption

Replicated

1349

Participants

N/A

Studies

Details PubMed

GWAS 2013-09-09

Family-based association analysis of alcohol dependence criteria and severity.

Wetherill L, Kapoor M et al.

Alcohol Clin Exp Res

Despite the high heritability of alcohol dependence (AD), the genes found to be associated with it a...

Alcohol dependence

Replicated

4969

Participants

N/A

Studies

Details PubMed

GWAS 2012-12-06

Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine codependence.

Zuo L, Zhang XY et al.

Alcohol Clin Exp Res

Alcohol and nicotine codependence can be considered as a more severe subtype of alcohol dependence. ...

Alcohol and nicotine co-dependence

Replicated

6880

Participants

N/A

Studies

Details PubMed

GWAS 2011-02-11

Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.

Kendler KS, Kalsi G et al.

Alcohol Clin Exp Res

While genetic influences on alcohol dependence (AD) are substantial, progress in the identification ...

Alcohol dependence

3169

Participants

N/A

Studies

Details PubMed

GWAS 2010-03-01

Genome-wide association study of alcohol dependence implicates a region on chromosome 11.

Edenberg HJ, Koller DL et al.

Alcohol Clin Exp Res

Alcohol dependence is a complex disease, and although linkage and candidate gene studies have identi...

Alcohol dependence

Replicated

2146

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Multivariate analyses reveal biological components related to neuronal signaling and immunity mediating EEG abnormalities in alcohol-dependent individuals from the COGA cohort.

Meda SA, Narayanan B et al.

Alcohol Clin Exp Res

Alcohol use disorder

2019-04-22

Biomarker and genomic risk factors for liver function test abnormality in hazardous drinkers.

Whitfield JB, Zhu G et al.

Alcohol Clin Exp Res

Gamma glutamyl transferase levels in excessive alcohol consumption

2018-12-27

Meta-Analysis of Genetic Influences on Initial Alcohol Sensitivity.

Edwards AC, Deak JD et al.

Alcohol Clin Exp Res

Initial alcohol sensitivity

2018-10-01

Risk locus identification ties alcohol withdrawal symptoms to SORCS2.

Smith AH, Ovesen PL et al.

Alcohol Clin Exp Res

Alcohol withdrawal symptoms

2018-09-25

Genomewide association study of alcohol dependence and related traits in a Thai population.

Gelernter J, Zhou H et al.

Alcohol Clin Exp Res

Alcohol dependence symptom count

2018-02-20

Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use.

Clark SL, Aberg KA et al.

Alcohol Clin Exp Res

Alcohol consumption

2015-07-04

Family-based association analysis of alcohol dependence criteria and severity.

Wetherill L, Kapoor M et al.

Alcohol Clin Exp Res

Alcohol dependence

2013-09-09

Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine codependence.

Zuo L, Zhang XY et al.

Alcohol Clin Exp Res

Alcohol and nicotine co-dependence

2012-12-06

Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.

Kendler KS, Kalsi G et al.

Alcohol Clin Exp Res

Alcohol dependence

2011-02-11

Genome-wide association study of alcohol dependence implicates a region on chromosome 11.

Edenberg HJ, Koller DL et al.

Alcohol Clin Exp Res

Alcohol dependence

2010-03-01