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GWAS Study

Risk locus identification ties alcohol withdrawal symptoms to SORCS2.

Smith AH, Ovesen PL, Skeldal S et al.

30252935 PubMed ID
GWAS Study Type
1231 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SA
Smith AH
OP
Ovesen PL
SS
Skeldal S
YS
Yeo S
JK
Jensen KP
OD
Olsen D
DN
Diazgranados N
ZH
Zhao H
FL
Farrer LA
GD
Goldman D
GS
Glerup S
KH
Kranzler HR
NA
Nykjaer A
GJ
Gelernter J
Chapter II

Abstract

Summary of the research findings

Efforts to promote the cessation of harmful alcohol use are hindered by the affective and physiological components of alcohol withdrawal (AW), which can include life-threatening seizures. Although previous studies of AW and relapse have highlighted the detrimental role of stress, little is known about genetic risk factors.

1,231 African American individuals

Chapter III

Study Statistics

Key metrics and study information

1231
Total Participants
GWAS
Study Type
Yes
Replicated
181 European American individuals
Replication Participants
African American or Afro-Caribbean, European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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