Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use.
Clark SL, Aberg KA, Nerella S et al.
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Abstract
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Methylome-wide association (MWAS) studies present a new way to advance the search for biological correlates for alcohol use. A challenge with methylation studies of alcohol involves the causal direction of significant methylation-alcohol associations. One way to address this issue is to combine MWAS data with genomewide association study (GWAS) data.
580 European ancestry cases, 39 European ancestry controls
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