Active: Clin Exp Allergy Clear all

GWAS 2021-08-30

A polygenic risk score for asthma in a large racially diverse population.

Sordillo JE, Lutz SM et al.

Clin Exp Allergy

Polygenic risk scores (PRSs) will have important utility for asthma and other chronic diseases as a ...

Asthma

401837

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-22

Identification of OCA2 as a novel locus for the co-morbidity of asthma-plus-eczema.

Margaritte-Jeannin P, Budu-Aggrey A et al.

Clin Exp Allergy

Numerous genes have been associated with the three most common allergic diseases (asthma, allergic r...

Asthma and eczema

8807

Participants

N/A

Studies

Details PubMed

GWAS 2019-08-04

Genome-wide interaction study of early-life smoking exposure on time-to-asthma onset in childhood.

Sugier PE, Sarnowski C et al.

Clin Exp Allergy

Asthma, a heterogeneous disease with variable age of onset, results from the interplay between genet...

Asthma (time to childhood onset) in early life tobacco smoke exposure

3187

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-29

Genome-wide association study of inhaled corticosteroid response in admixed children with asthma.

Hernandez-Pacheco N, Farzan N et al.

Clin Exp Allergy

Inhaled corticosteroids (ICS) are the most widely prescribed and effective medication to control ast...

Asthma exacerbations in inhaled corticosteroid treatment

Replicated

3044

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-18

Longitudinal analysis to better characterize Asthma-COPD Overlap Syndrome (ACOS): Findings from an adult asthma cohort in Korea (COREA).

Park SY, Jung H et al.

Clin Exp Allergy

Asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS), which has received much...

Adult asthma

7271

Participants

N/A

Studies

Details PubMed

GWAS 2018-05-22

Novel genes and insights in complete asthma remission.

Vonk JM, Nieuwenhuis MAE et al.

Clin Exp Allergy

Asthma is a chronic respiratory disease without a cure, although there exists spontaneous remission....

Clinical remission in asthma

Replicated

1246

Participants

N/A

Studies

Details PubMed

GWAS 2017-01-11

Genomewide association study of peanut allergy reproduces association with amino acid polymorphisms in HLA-DRB1.

Martino DJ, Ashley S et al.

Clin Exp Allergy

Genetic variants for IgE-mediated peanut allergy are yet to be fully characterized and to date only ...

Peanut allergy

Replicated

5507

Participants

N/A

Studies

Details PubMed

GWAS 2014-11-27

A common variant in RAB27A gene is associated with fractional exhaled nitric oxide levels in adults.

Bouzigon E, Nadif R et al.

Clin Exp Allergy

Exhaled nitric oxide (FeNO) is a biomarker for eosinophilic inflammation in the airways and for resp...

Fractional exhaled nitric oxide levels

Replicated

10519

Participants

N/A

Studies

Details PubMed

GWAS 2013-04-01

Genome-wide association study of body mass index in 23 000 individuals with and without asthma.

Melén E, Granell R et al.

Clin Exp Allergy

Both asthma and obesity are complex disorders that are influenced by environmental and genetic facto...

Body mass index in non-asthmatics

Replicated

14976

Participants

N/A

Studies

Details PubMed

GWAS 2012-12-04

HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.

Lasky-Su J, Himes BE et al.

Clin Exp Allergy

Asthma is a common chronic respiratory disease in children and adults. An important genetic componen...

Asthma

Replicated

16260

Participants

N/A

Studies

Details PubMed

GWAS 2009-02-01

Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis.

Kim SH, Cho BY et al.

Clin Exp Allergy

Toluene diisocyanate (TDI) is the most important cause of occupational asthma, but the genetic mecha...

Asthma (toluene diisocyanate-induced)

347

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A polygenic risk score for asthma in a large racially diverse population.

Sordillo JE, Lutz SM et al.

Clin Exp Allergy

Asthma

2021-08-30

Identification of OCA2 as a novel locus for the co-morbidity of asthma-plus-eczema.

Margaritte-Jeannin P, Budu-Aggrey A et al.

Clin Exp Allergy

Asthma and eczema

2021-06-22

Genome-wide interaction study of early-life smoking exposure on time-to-asthma onset in childhood.

Sugier PE, Sarnowski C et al.

Clin Exp Allergy

Asthma (time to childhood onset) in early life tobacco smoke exposure

2019-08-04

Genome-wide association study of inhaled corticosteroid response in admixed children with asthma.

Hernandez-Pacheco N, Farzan N et al.

Clin Exp Allergy

Asthma exacerbations in inhaled corticosteroid treatment

2019-01-29

Longitudinal analysis to better characterize Asthma-COPD Overlap Syndrome (ACOS): Findings from an adult asthma cohort in Korea (COREA).

Park SY, Jung H et al.

Clin Exp Allergy

Adult asthma

2019-01-18

Novel genes and insights in complete asthma remission.

Vonk JM, Nieuwenhuis MAE et al.

Clin Exp Allergy

Clinical remission in asthma

2018-05-22

Genomewide association study of peanut allergy reproduces association with amino acid polymorphisms in HLA-DRB1.

Martino DJ, Ashley S et al.

Clin Exp Allergy

Peanut allergy

2017-01-11

A common variant in RAB27A gene is associated with fractional exhaled nitric oxide levels in adults.

Bouzigon E, Nadif R et al.

Clin Exp Allergy

Fractional exhaled nitric oxide levels

2014-11-27

Genome-wide association study of body mass index in 23 000 individuals with and without asthma.

Melén E, Granell R et al.

Clin Exp Allergy

Body mass index in non-asthmatics

2013-04-01

HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.

Lasky-Su J, Himes BE et al.

Clin Exp Allergy

Asthma

2012-12-04

Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis.

Kim SH, Cho BY et al.

Clin Exp Allergy

Asthma (toluene diisocyanate-induced)

2009-02-01