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GWAS Study

A common variant in RAB27A gene is associated with fractional exhaled nitric oxide levels in adults.

Bouzigon E, Nadif R, Thompson EE et al.

25431337 PubMed ID
GWAS Study Type
10519 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BE
Bouzigon E
NR
Nadif R
TE
Thompson EE
CM
Concas MP
KS
Kuldanek S
DG
Du G
BM
Brossard M
LN
Lavielle N
SC
Sarnowski C
VA
Vaysse A
DP
Dessen P
VD
van der Valk RJ
DL
Duijts L
HA
Henderson AJ
JV
Jaddoe VW
DJ
de Jongste JC
CS
Casula S
BG
Biino G
DM
Dizier MH
PI
Pin I
MR
Matran R
LM
Lathrop M
PM
Pirastu M
DF
Demenais F
OC
Ober C
Chapter II

Abstract

Summary of the research findings

Exhaled nitric oxide (FeNO) is a biomarker for eosinophilic inflammation in the airways and for responsiveness to corticosteroids in asthmatics.

610 European ancestry adult individuals, 601 Hutterite (founder/genetic isolate) adult individuals

Chapter III

Study Statistics

Key metrics and study information

10519
Total Participants
GWAS
Study Type
Yes
Replicated
450 Talana (founder/genetic isolate) adult individuals, 8,858 European ancestry children
Replication Participants
European
Ancestry
Italy, U.S., France
Recruitment Country
Chapter IV

AI-Generated Summary

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