HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.
Lasky-Su J, Himes BE, Raby BA et al.
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Abstract
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Asthma is a common chronic respiratory disease in children and adults. An important genetic component to asthma susceptibility has long been recognized, most recently through the identification of several genes (e.g., ORMDL3, PDE4D, HLA-DQ, and TLE4) via genome-wide association studies.
Up to 1,238 European ancestry cases, up to 2,617 European ancestry controls
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